Thaumatin | CAS No. 53850-34-3

Thaumatin

Basic Information

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CAS Number

53850-34-3

Molecular Formula

C19H29N3O3S

Molecular Weight

379.5 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Boiling Point

325.7±15.0 °C at 760 mmHg

Density

1.0±0.1 g/cm3

Water Solubility

Soluble in water (25 mg/ml), and 60% ethanol. Insoluble in ether, and benzene .

Flash Point

165.0±16.9 °C

Vapor Pressure

0.0±1.5 mmHg at 25°C

SMILES

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CC(=O)NC1=CC=C(C=C1)S(=O)(=O)N2CCN(CC2)C3CCCCCC3

InChI

InChI=1S/C19H29N3O3S/c1-16(23)20-17-8-10-19(11-9-17)26(24,25)22-14-12-21(13-15-22)18-6-4-2-3-5-7-18/h8-11,18H,2-7,12-15H2,1H3,(H,20,23)

InChIKey

IVPOQXWRUMMORK-UHFFFAOYSA-N

LogP

2.6741

Topological Polar Surface Area

69.72 Å²

Hydrogen Bond Donor/Acceptor

1 / 6

Complexity

551

Synonyms & References

English

AKOS001637661
N-[4-(4-cycloheptylpiperazine-1-sulfonyl)phenyl]acetamide
N-[4-(4-cycloheptylpiperazin-1-yl)sulfonylphenyl]acetamide
N-[4-(4-cycloheptylpiperazin-1-yl)sulonylphenyl]acetamide
Thaumatin B, recombinant
Oprea1_669084
53850-34-3
THAUMATIN
Oprea1_565606
CHEBI:175005
N~1~-{4-[(4-CYCLOHEPTYLPIPERAZINO)SULFONYL]PHENYL}ACETAMIDE
Thaumatins
Thaumatin
A mixture in the ratio 2:1 of two polypeptides, thaumatin I and II, each consisting of 207 amino acid residues and having a molecular wei
A mixture in the ratio 2:1 of two polypeptides, thaumatin I and II, each consisting of 207 amino acid residues and having a molecular weight of about 22,000, extracted from the aril of the tropical fruit Thaumatococcus daniellii
FEMA No. 3732
HSDB 3927
Talin
Thaumatin [BAN]

MDL Number

MFCD00132420

FAQ

What are the physical and chemical properties of Thaumatin (CAS: 53850-34-3)?

Thaumatin (CAS: 53850-34-3) is a sweet protein with a crystalline form. It has a molecular weight of approximately 28,000 Da. Thaumatin is highly soluble in water and has good stability under acidic and alkaline conditions. Its sweetness is about 2000 times that of sucrose, making it a valuable sweetener. Chemically, it is resistant to enzymatic degradation and heat treatment, which contributes to its stability in food products.

How is Thaumatin (CAS: 53850-34-3) typically synthesized?

Thaumatin (CAS: 53850-34-3) is typically synthesized through fermentation using genetically modified yeast or bacteria. The process involves genetic engineering to produce thaumatin-like proteins, which are then purified and crystallized. Commonly used yeast strains include Pichia pastoris. The fermentation process is optimized to achieve high yield and selectivity, with the final product being purified through steps like filtration, chromatography, and lyophilization.

What industries use Thaumatin (CAS: 53850-34-3)?

Thaumatin (CAS: 53850-34-3) is primarily used in the food and beverage industry as a natural sweetener. It is also applicable in the pharmaceutical industry for its potential as a sweetener in low-calorie and diabetic-friendly products. Additionally, it is used in the cosmetic industry as a flavor enhancer and in the health and wellness sector for its perceived benefits in weight management.

What precautions should be taken when handling Thaumatin (CAS: 53850-34-3)?

When handling Thaumatin (CAS: 53850-34-3), it is important to wear appropriate personal protective equipment (PPE) such as gloves and safety goggles. Work should be conducted in a well-ventilated environment or a fume hood to prevent inhalation of dust. Spills should be cleaned up immediately using appropriate absorbent materials, and proper waste disposal procedures should be followed. Always refer to the Safety Data Sheet (SDS) for detailed information on handling and storage.