(2R)-2-Amino-3-(1H-indol-3-yl)-1-propanol

Basic Information

View in Editor

CAS Number

52485-52-6

Molecular Formula

C11H14N2O

Molecular Weight

190.25 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

86-89 °C

Density

1.2450

Specific Rotation

-20.5 º (c=1 in methanol)

SMILES

View in Editor

C1=CC=C2C(=C1)C(=CN2)CC(CO)N

InChI

InChI=1S/C11H14N2O/c12-9(7-14)5-8-6-13-11-4-2-1-3-10(8)11/h1-4,6,9,13-14H,5,7,12H2/t9-/m1/s1

InChIKey

UDQCRUSSQAXPJY-SECBINFHSA-N

LogP

1.03

Topological Polar Surface Area

62.04 Å²

Hydrogen Bond Donor/Acceptor

4 / 3

Complexity

186

Synonyms & References

English

UDQCRUSSQAXPJY-SECBINFHSA-N
SCHEMBL1177116
AKOS000301896
CHEMBL1222397
r-tryptophanol
MFCD00270220
D-Tryptophanol
AS-56553
D-Tryptophanol, 97%
(R)-Tryptophanol
52485-52-6
CS-W015884
(D)-tryptophanol
(2R)-2-amino-3-(1H-indol-3-yl)-propan-1-ol
(R)-2-Amino-3-(1H-indol-3-yl)propan-1-ol
DTXSID70370101
A829109
(R)-2-Amino-3-(1H-indol-3-yl)-propan-1-ol
(2R)-2-amino-3-(1H-indol-3-yl)propan-1-ol
A51089
D-Tryptophanol*HCl
1H-Indole-3-propanol,b-amino-, (R)-

MDL Number

MFCD00270220

FAQ

What are the physical and chemical properties of (2R)-2-Amino-3-(1H-indol-3-yl)-1-propanol (CAS: 52485-52-6)?

(2R)-2-Amino-3-(1H-indol-3-yl)-1-propanol is a colorless solid with a molecular weight of approximately 212.26 g/mol. It has a solubility of about 10 mg/mL in water. Chemically, it is reactive towards strong acids and bases. It crystallizes in a monoclinic form and has good solubility in organic solvents like methanol and ethanol.

How is (2R)-2-Amino-3-(1H-indol-3-yl)-1-propanol (CAS: 52485-52-6) typically synthesized?

(2R)-2-Amino-3-(1H-indol-3-yl)-1-propanol is synthesized via a multi-step process involving the reaction of 3-aminopropanol with 1H-indole. The synthesis typically employs catalytic hydrogenation and condensation reactions, yielding a product with high selectivity and good yield under controlled conditions. Commonly, palladium catalysts are used in the hydrogenation step.

What industries use (2R)-2-Amino-3-(1H-indol-3-yl)-1-propanol (CAS: 52485-52-6)?

(2R)-2-Amino-3-(1H-indol-3-yl)-1-propanol is utilized in the pharmaceutical industry for its role as a precursor in the synthesis of indole derivatives with medicinal properties. It is also found in research applications related to polymer science and the development of sensors and semiconductors.

What precautions should be taken when handling (2R)-2-Amino-3-(1H-indol-3-yl)-1-propanol (CAS: 52485-52-6)?

When handling (2R)-2-Amino-3-(1H-indol-3-yl)-1-propanol, it is crucial to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coats. Work should be conducted in a well-ventilated area or fume hood to minimize inhalation risks. Spills should be cleaned up using absorbent materials and disposed of according to proper waste disposal procedures. Always refer to the Safety Data Sheet (SDS) for detailed safety information.