Compound Q&A

How is (2R)-2-Amino-3-(1H-indol-3-yl)-1-propanol (CAS: 52485-52-6) typically synthesized?

Answer

(2R)-2-Amino-3-(1H-indol-3-yl)-1-propanol
(2R)-2-Amino-3-(1H-indol-3-yl)-1-propanol is synthesized via a multi-step process involving the reaction of 3-aminopropanol with 1H-indole. The synthesis typically employs catalytic hydrogenation and condensation reactions, yielding a product with high selectivity and good yield under controlled conditions. Commonly, palladium catalysts are used in the hydrogenation step.

About

CAS No 52485-52-6
English Name (2R)-2-Amino-3-(1H-indol-3-yl)-1-propanol
Molecular Formula C11H14N2O
Molecular Weight 190.25 g/mol
SMILES C1=CC=C2C(=C1)C(=CN2)CC(CO)N
InChIKey UDQCRUSSQAXPJY-SECBINFHSA-N
Last Updated: 2025-10-10 21:10

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