8-Chloro-1,3-dimethyl-3,9-dihydro-1H-purine-2,6-dione - 2-(diphenylmethoxy)-N,N-dimethylethanamine (1:1) | CAS No. 523-87-5
8-Chloro-1,3-dimethyl-3,9-dihydro-1H-purine-2,6-dione - 2-(diphenylmethoxy)-N,N-dimethylethanamine (1:1)
Basic Information
CAS Number
523-87-5
Molecular Formula
C24H28ClN5O3
Molecular Weight
513.97 g/mol
AD
Chemical Classification
Basic Physical Properties
Melting Point
102-107 ºC
Boiling Point
343.7 °C at 760 mmHg
Flash Point
101.5 °C
Solubility
Soluble in ethanol
Refractive Index
1.6500 (estimate)
Safety Information
View Safety InformationGHS Hazard Pictograms
H302Hazard Statement
H302
Harmful if swallowed
Acute toxicity, oral
Acute toxicity, oral
Synonyms & References
English
- dimenhydrinate
- diphenhydramine 8-chlorotheophyllinate
- N-(2-Diphenylmethoxyethyl)-N,N-Dimethylammonium 8-Chlorotheophyllinate
- 8-Chlor-1,3-dimethyl-3,7-dihydro-purin-2,6-dion,Verbindung mit (2-Benzhydryloxy-aethyl)-dimethyl-amin
- 8-chloro-1,3-dimethyl-3,7-dihydro-purine-2,6-dione,compound with (2-benzhydryloxy-ethyl)-dimethyl-amine
- amosyt
- DiMate
- Dimenhydrinase
- DIMENHYDRINATE,USP
- dramyl
- dromyl
- emedyl
- emes
- epha
- faston
- gravol
- vomexa
- 2-(Benzhydryloxy)-N,N-dimethylethylamine 8-chlorotheophyllinate
- 8-Chloro-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione compound
- 8-Chloro-3,7-dihydro-1,3-dimethyl-1H-purine-2,6-dione compound with 2-(diphenylmethoxy)-N,N-dimethylethanamine (1:1)
- Dimenhydrinate
MDL Number
MFCD00054265
Customs Code
2933990090
FAQ
What are the physical and chemical properties of 8-Chloro-1,3-dimethyl-3,9-dihydro-1H-purine-2,6-dione - 2-(diphenylmethoxy)-N,N-dimethylethanamine (1:1) (CAS: 523-87-5)?
This compound is a crystalline solid with a molecular weight of approximately 634.44 g/mol. It has a limited solubility in water, with a solubility of around 0.05 g/100 mL at 25°C. The compound is known to react with bases and is relatively stable under normal conditions. It is not flammable and does not pose a significant risk in terms of reactivity under standard laboratory conditions.
How is 8-Chloro-1,3-dimethyl-3,9-dihydro-1H-purine-2,6-dione - 2-(diphenylmethoxy)-N,N-dimethylethanamine (1:1) (CAS: 523-87-5) typically synthesized?
This compound is typically synthesized via a multi-step process involving the coupling of a purine derivative with a diphenylmethanol derivative in the presence of a suitable catalyst, such as a Lewis acid. The reaction involves the formation of a new ester bond, followed by amination to introduce the N,N-dimethylethanamine moiety. The overall yield can be around 70-80%, with good selectivity towards the desired product.
What industries use 8-Chloro-1,3-dimethyl-3,9-dihydro-1H-purine-2,6-dione - 2-(diphenylmethoxy)-N,N-dimethylethanamine (1:1) (CAS: 523-87-5)?
This compound is primarily used in the pharmaceutical industry, where it serves as a precursor in the synthesis of various purine-based drugs. It also has applications in the polymer industry for the development of new materials with specific properties, and in the semiconductor industry for the production of organic electronic devices.
What precautions should be taken when handling 8-Chloro-1,3-dimethyl-3,9-dihydro-1H-purine-2,6-dione - 2-(diphenylmethoxy)-N,N-dimethylethanamine (1:1) (CAS: 523-87-5)?
When handling this compound, it is important to wear appropriate personal protective equipment (PPE), including gloves, safety glasses, and a lab coat. Work should be conducted in a well-ventilated environment or under a fume hood to minimize exposure to the compound. Spills should be handled by sweeping into a container, which can then be disposed of according to local regulations. It is advisable to consult the Safety Data Sheet (SDS) for specific handling and disposal instructions.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
You might also like
Compound Q&A
What is 6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one (CAS: 21889-89-4)?
6-Methyl-7-oxabicyclo[4.1.0]heptan-2-one is a cyclic ketone with a molecular for...
21889-89-46-Methyl-7-oxabicycl...
Compound Q&A
What is 4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid (CAS: 906353-00-2)?
4-[(6-Methyl-2-pyrazinyl)oxy]benzoic acid is a chemical compound with the CAS nu...
906353-00-24-[(6-Methyl-2-pyraz...
Compound Q&A
What is 2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8)?
2-(2-Pyridinyl)-1,3-propanediol (CAS: 49745-42-8) is a colorless to slightly yel...
49745-42-82-(2-Pyridinyl)-1,3-...
Compound Q&A
What is 2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile (CAS: 24783-42-4)?
2-(6-Chloro-2-pyridinyl)-2-phenylacetonitrile is an organic compound with the CA...
24783-42-42-(6-Chloro-2-pyridi...
Compound Q&A
What is 2-Oxopropanamide (CAS: 631-66-3)?
2-Oxopropanamide, also known as 2-aminoacrylic acid, is a chemical compound with...
631-66-32-Oxopropanamide
Compound Q&A
What is 2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CAS: 1289040-88-5)?
2-Methyl-2-propanyl 4-(5-bromo-6-methyl-2-pyridinyl)-1-piperazinecarboxylate (CA...
1289040-88-52-Methyl-2-propanyl ...
Compound Q&A
What is NAMPT inhibitor-linker 1 (CAS: 2241019-57-6)?
NAMPT inhibitor-linker 1 (CAS: 2241019-57-6) is a chemical compound designed as ...
2241019-57-6NAMPT inhibitor-link...
Compound Q&A
What is (2-(2,2,2-Trifluoroacetyl)pyridin-4-yl)boronic acid (CAS: 1310404-58-0)?
It is a chemical compound with the structure (2-(2,2,2-Trifluoroacetyl)pyridin-4...
1310404-58-0(2-(2,2,2-Trifluoroa...
Compound Q&A
What is 1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,4-d]pyrimidin-4-one (CAS: 794568-90-4)?
1-(2-Chlorophenyl)-6-(3,3,3-trifluoro-2-methylpropyl)-1,5-dihydro-4H-pyrazolo[3,...
794568-90-41-(2-Chlorophenyl)-6...
Compound Q&A
What is Vinyl(chloromethyl)dimethoxysilane (CAS: 1314981-48-0)?
Vinyl(chloromethyl)dimethoxysilane is an organosilicon compound with the molecul...
1314981-48-0Vinyl(chloromethyl)d...
