Compound Q&A

How is 8-Chloro-1,3-dimethyl-3,9-dihydro-1H-purine-2,6-dione - 2-(diphenylmethoxy)-N,N-dimethylethanamine (1:1) (CAS: 523-87-5) typically synthesized?

Answer

8-Chloro-1,3-dimethyl-3,9-dihydro-1H-purine-2,6-dione - 2-(diphenylmethoxy)-N,N-dimethylethanamine (1:1)
This compound is typically synthesized via a multi-step process involving the coupling of a purine derivative with a diphenylmethanol derivative in the presence of a suitable catalyst, such as a Lewis acid. The reaction involves the formation of a new ester bond, followed by amination to introduce the N,N-dimethylethanamine moiety. The overall yield can be around 70-80%, with good selectivity towards the desired product.

About

CAS No 523-87-5
English Name 8-Chloro-1,3-dimethyl-3,9-dihydro-1H-purine-2,6-dione - 2-(diphenylmethoxy)-N,N-dimethylethanamine (1:1)
Molecular Formula C24H28ClN5O3
Molecular Weight 513.97 g/mol
SMILES [O-]C(=O)Cn1c(=O)c2[nH]c(nc2n(c1=O)C)Cl.C[NH+](CCOC(c1ccccc1)c1ccccc1)C
InChIKey NFLLKCVHYJRNRH-UHFFFAOYSA-N
Last Updated: 2025-09-19 21:14

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