2-Methyl-2-propanyl O-(2-methyl-2-propanyl)-L-serinate hydrochloride (1:1)

Basic Information

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CAS Number

51537-21-4

Molecular Formula

C11H24ClNO3

Molecular Weight

253.77 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

159-162°C

Specific Rotation

-9 ~ -11° (c=1,H2O)

SMILES

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CC(C)(C)OCC(C(=O)OC(C)(C)C)N.Cl

InChI

InChI=1S/C11H23NO3.ClH/c1-10(2,3)14-7-8(12)9(13)15-11(4,5)6;/h8H,7,12H2,1-6H3;1H/t8-;/m0./s1

InChIKey

RDWZQVGVBTYCBD-QRPNPIFTSA-N

LogP

1.8922999999999996

Topological Polar Surface Area

61.55 Å²

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

213

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

O-tert-Butyl-L-serine tert-butyl ester hydrochloride
H-Ser(tBu)-OtBu hydrochloride
O-tert-Butyl-L-serine tert-butyl ester hydrochloride, >=98.0% (AT)
(S)-TERT-BUTYL 2-AMINO-3-(TERT-BUTOXY)PROPANOATE HCL
tert-butyl (2S)-2-amino-3-[(2-methylpropan-2-yl)oxy]propanoate hydrochloride
SCHEMBL318950
O-t-butylserine-t-butyl ester hydrochloride
MFCD00034850
H-Ser(tBu)-OtBu HCl
O-tert-Butyl-L-serine tert-butyl ester HCl
HY-W013373
tert-butyl (2S)-2-amino-3-[(2-methylpropan-2-yl)oxy]propanoate;hydrochloride
O-tert-Butyl-L-serine t-butyl ester hydrochloride
(s)-tert-butyl 2-amino-3-tert-butoxypropanoate hydrochloride
H-Ser(tBu)-OtBu.HCl
RDWZQVGVBTYCBD-QRPNPIFTSA-N
tert-butyl (2S)-2-amino-3-(tert-butoxy)propanoate hydrochloride
CS-W014089
51537-21-4
H-L-Ser(tBu)-OtBu HCl
AKOS015998700
EN300-6477387
(S)-2-amino-3-tert-butoxy-propionic acid tert-butyl ester hydrochloride
tert-Butyl O-(tert-butyl)-L-serinate hydrochloride
O-t-Butyl-L-serine t-butyl ester hydrochloride
tert-butyl (2S)-2-amino-3-tert-butoxy-propanoate hydrochloride
DS-1815
O-tert-butyl L-serine tert-butyl ester hydrochloride
AM20100259
(S)-tert-Butyl 2-amino-3-(tert-butoxy)propanoate hydrochloride
L-Serine,O-(1,1-dimethylethyl)-, 1,1-dimethylethyl ester, hydrochloride (1:1)

MDL Number

MFCD00034850

FAQ

What are the physical and chemical properties of 2-Methyl-2-propanyl O-(2-methyl-2-propanyl)-L-serinate hydrochloride (CAS: 51537-21-4)?

2-Methyl-2-propanyl O-(2-methyl-2-propanyl)-L-serinate hydrochloride is a white crystalline solid with a molecular weight of approximately 444.1 g/mol. It has a hydrophobic nature and good solubility in organic solvents such as ethanol and acetone. This compound is relatively stable under normal conditions but can react with strong bases. It is not flammable and does not pose a significant risk in handling under standard laboratory conditions.

How is 2-Methyl-2-propanyl O-(2-methyl-2-propanyl)-L-serinate hydrochloride (CAS: 51537-21-4) typically synthesized?

This compound can be synthesized through a multi-step process involving the condensation of 2-methyl-2-propanol with L-serine, followed by the formation of the corresponding O-alkylation product and its reaction with hydrochloric acid to form the hydrochloride salt. The reaction is typically carried out in the presence of a catalyst and under mild conditions to ensure high selectivity and yield.

What industries use 2-Methyl-2-propanyl O-(2-methyl-2-propanyl)-L-serinate hydrochloride (CAS: 51537-21-4)?

This compound is primarily used in the pharmaceutical industry for its potential as a chiral intermediate in the synthesis of drugs. It can also be utilized in the chemical industry as a reagent in various organic synthesis reactions. Additionally, it has applications in the development of sensors and semiconductors due to its unique chemical properties.

What precautions should be taken when handling 2-Methyl-2-proanyl O-(2-methyl-2-propanyl)-L-serinate hydrochloride (CAS: 51537-21-4)?

When handling this compound, it is essential to wear appropriate personal protective equipment (PPE), including gloves, safety glasses, and a lab coat. Handle the compound in a well-ventilated area or a fume hood to minimize exposure to vapors. Proper storage should be in a cool, dry place away from incompatible materials. In case of a spill, immediately clean up using appropriate safety protocols and consult the Safety Data Sheet (SDS) for detailed instructions.