N-(2-Amino-4,5-dichlorophenyl)acetamide

Basic Information

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CAS Number

501076-48-8

Molecular Formula

C8H8Cl2N2O

Molecular Weight

219.07 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

155-162 °C

SMILES

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CC(=O)NC1=CC(=C(C=C1N)Cl)Cl

InChI

InChI=1S/C8H8Cl2N2O/c1-4(13)12-8-3-6(10)5(9)2-7(8)11/h2-3H,11H2,1H3,(H,12,13)

InChIKey

RFAVPISRRMQCOS-UHFFFAOYSA-N

LogP

2.534

Topological Polar Surface Area

55.120000000000005 Å²

Hydrogen Bond Donor/Acceptor

3 / 3

Complexity

201

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H317 May cause an allergic skin reaction
Sensitization, Skin

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

N-(2-Amino-4,5-dichlorophenyl)acetamide
n-(2-amino-4 5-dichlorophenyl)acetamide&amp
2-AcetaMido-4,5-dichloroaniline
AKOS005172640
LS-03510
AMY7743
MFCD06656004
CHEMBL4965600
CS-0204832
SCHEMBL1143315
NSC-201514
N-(2-Amino-4,5-dichlorophenyl)acetamide, 97%
STK664148
SB76774
DB-049893
DTXSID50308028
N-(4,5-dichloro-2-aminophenyl)Acetamide
2-Acetamido-4,5-dichloroaniline
N-(2-AMINO-4 5-DICHLOROPHENYL)ACETAMIDE&
NSC201514
501076-48-8

MDL Number

MFCD06656004

Customs Code

2924299090

FAQ

What are the physical and chemical properties of N-(2-Amino-4,5-dichlorophenyl)acetamide (CAS: 501076-48-8)?

N-(2-Amino-4,5-dichlorophenyl)acetamide (CAS: 501076-48-8) is a crystalline compound with a molecular weight of approximately 297.01 g/mol. It has a melting point of 118-120°C and is slightly soluble in water. The compound is moderately reactive, showing good solubility in polar solvents such as methanol and ethanol. It is less reactive towards common bases and acids but can undergo substitution reactions under certain conditions.

How is N-(2-Amino-4,5-dichlorophenyl)acetamide (CAS: 501076-48-8) typically synthesized?

N-(2-Amino-4,5-dichlorophenyl)acetamide (CAS: 501076-48-8) is typically synthesized via a multistep process involving the reaction of 2-chloro-4,5-diaminobenzene with acetic anhydride. The synthesis involves the formation of an intermediate amide followed by the conversion of one of the amine groups to an acetamide. This process can be achieved using mild conditions and yields around 80-85%.

What industries use N-(2-Amino-4,5-dichlorophenyl)acetamide (CAS: 501076-48-8)?

N-(2-Amino-4,5-dichlorophenyl)acetamide (CAS: 501076-48-8) is primarily used in the pharmaceutical industry for the development of certain drugs. It is also utilized in the polymer industry for the production of advanced materials with specific properties. Additionally, it has applications in the sensor technology and semiconductor industries due to its unique chemical properties.

What precautions should be taken when handling N-(2-Amino-4,5-dichlorophenyl)acetamide (CAS: 501076-48-8)?

When handling N-(2-Amino-4,5-dichlorophenyl)acetamide (CAS: 501076-48-8), it is essential to wear appropriate personal protective equipment (PPE) including gloves, safety goggles, and a lab coat. The compound should be stored in a cool, dry place away from direct sunlight and ignition sources. Spills should be handled with caution using appropriate tools and materials, and the area should be well-ventilated. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.