Compound Q&A

How is N-(2-Amino-4,5-dichlorophenyl)acetamide (CAS: 501076-48-8) typically synthesized?

Answer

N-(2-Amino-4,5-dichlorophenyl)acetamide
N-(2-Amino-4,5-dichlorophenyl)acetamide (CAS: 501076-48-8) is typically synthesized via a multistep process involving the reaction of 2-chloro-4,5-diaminobenzene with acetic anhydride. The synthesis involves the formation of an intermediate amide followed by the conversion of one of the amine groups to an acetamide. This process can be achieved using mild conditions and yields around 80-85%.

About

English Name N-(2-Amino-4,5-dichlorophenyl)acetamide
Molecular Formula C8H8Cl2N2O
Molecular Weight 219.07 g/mol
SMILES CC(=O)NC1=CC(=C(C=C1N)Cl)Cl
InChIKey RFAVPISRRMQCOS-UHFFFAOYSA-N
Last Updated: 2026-03-11 12:33

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