N-(2-Amino-4,5-dichlorophenyl)acetamide(CAS: 501076-48-8)

N-(2-Amino-4,5-dichlorophenyl)acetamide (CAS: 501076-48-8) is a crystalline compound with a molecular weight of approximately 297.01 g/mol. It has a melting point of 118-120°C and is slightly soluble in water. The compound is moderately reactive, showing good solubility in polar solvents such as methanol and ethanol. It is less reactive towards common bases and acids but can undergo substitution reactions under certain conditions.

N-(2-Amino-4,5-dichlorophenyl)acetamide (CAS: 501076-48-8) is typically synthesized via a multistep process involving the reaction of 2-chloro-4,5-diaminobenzene with acetic anhydride. The synthesis involves the formation of an intermediate amide followed by the conversion of one of the amine groups to an acetamide. This process can be achieved using mild conditions and yields around 80-85%.

N-(2-Amino-4,5-dichlorophenyl)acetamide (CAS: 501076-48-8) is primarily used in the pharmaceutical industry for the development of certain drugs. It is also utilized in the polymer industry for the production of advanced materials with specific properties. Additionally, it has applications in the sensor technology and semiconductor industries due to its unique chemical properties.

When handling N-(2-Amino-4,5-dichlorophenyl)acetamide (CAS: 501076-48-8), it is essential to wear appropriate personal protective equipment (PPE) including gloves, safety goggles, and a lab coat. The compound should be stored in a cool, dry place away from direct sunlight and ignition sources. Spills should be handled with caution using appropriate tools and materials, and the area should be well-ventilated. Always refer to the Safety Data Sheet (SDS) for detailed handling and emergency procedures.