5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-chromen-4-one

Basic Information

View in Editor

CAS Number

491-71-4

Molecular Formula

C16H12O6

Molecular Weight

300.27 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Physical State

Yellow powder

Melting Point

>300°C (dec.)

Boiling Point

574.3°C at 760 mmHg

Density

1.512

Flash Point

219.4°C

Solubility

Methanol; DMSO

Refractive Index

1.697

SMILES

View in Editor

COc1cc(ccc1O)c2cc(=O)c3c(O)cc(O)cc3o2

InChI

InChI=1S/C16H12O6/c1-21-14-4-8(2-3-10(14)18)13-7-12(20)16-11(19)5-9(17)6-15(16)22-13/h2-7,17-19H,1H3

InChIKey

SCZVLDHREVKTSH-UHFFFAOYSA-N

LogP

2.5854

Topological Polar Surface Area

100.13000000000001 Å²

Hydrogen Bond Donor/Acceptor

3 / 6

Complexity

462

Safety Information

View Safety Information

Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Storage Conditions

2-8℃

Synonyms & References

English

5-7-Dihydroxy-2--4-hydroxy-3-methoxyphenyl--4H-1-benzopyran-4-one
4H-1-Benzopyran-4-one, 5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-
Chrysoeriol
5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-1-benzopyran-4-one
5,7-dihydroxy-2-(4-hydroxy-3-methoxyphenyl)chromen-4-one
CHRYSOERIOL(AS) PrintBack
3'-Methoxyapigenin
3'-O-Methylluteolin
3'-O-Methyluteolin
Chryseriol
EINECS 207-742-6
Luteolin 3'-methyl ether
3'-Methoxyapigenin,3'-O-Methylluteolin,Luteolin 3'-methyl ether,Chrysoriol,5,7,4'-Trihydroxy-3'-meth...

MDL Number

MFCD00016780

FAQ

What are the physical and chemical properties of 5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-chromen-4-one (CAS: 491-71-4)?

5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-chromen-4-one is a yellow crystalline compound with a molecular weight of approximately 318.23 g/mol. It is sparingly soluble in water but soluble in organic solvents like ethanol and acetone. The compound is moderately reactive and can undergo hydrolysis and condensation reactions under certain conditions.

How is 5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-chromen-4-one (CAS: 491-71-4) typically synthesized?

5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-chromen-4-one can be synthesized through multistep organic reactions including condensation, acylation, and reduction. Commonly, the synthesis involves the condensation of appropriate aromatic aldehydes and phenols followed by reduction to form the chromone skeleton. This compound is often synthesized using catalytic hydrogenation under pressure with palladium catalysts.

What industries use 5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-chromen-4-one (CAS: 491-71-4)?

5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-chromen-4-one is used in the pharmaceutical industry for the development of drugs targeting various ailments. It is also used in the polymer industry for synthesizing functional polymers and in the sensor industry for developing chemical and biological sensors. Additionally, it can be employed in the semiconductor industry for manufacturing organic light-emitting diodes (OLEDs).

What precautions should be taken when handling 5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-chromen-4-one (CAS: 491-71-4)?

Proper personal protective equipment (PPE) is essential when handling 5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-4H-chromen-4-one (CAS: 491-71-4), including gloves, lab coat, and safety goggles. The compound should be handled in a well-ventilated fume hood to minimize inhalation. Spills should be managed with appropriate absorbents, and the area should be cleaned thoroughly. Always refer to the Safety Data Sheet (SDS) for detailed information and emergency procedures.