2,4,5-Triphenyl-1H-imidazole

Basic Information

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CAS Number

484-47-9

Molecular Formula

C21H16N2

Molecular Weight

296.37 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Basic Physical Properties

Melting Point

274-278 °C

Boiling Point

508.6℃ at 760 mmHg

Water Solubility

Soluble in methanol. Insoluble in water.

Flash Point

272.6±7.9 °C

Refractive Index

1.8000 (estimate)

Vapor Pressure

0.0±1.3 mmHg at 25°C

SMILES

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C1=CC=C(C=C1)C2=C(N=C(N2)C3=CC=CC=C3)C4=CC=CC=C4

InChI

InChI=1S/C21H16N2/c1-4-10-16(11-5-1)19-20(17-12-6-2-7-13-17)23-21(22-19)18-14-8-3-9-15-18/h1-15H,(H,22,23)

InChIKey

RNIPJYFZGXJSDD-UHFFFAOYSA-N

LogP

5.410700000000004

Topological Polar Surface Area

28.68 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

351

Synonyms & References

English

SR-01000510787-1
A827535
2,4,5-Triphenylimidazole, 98%
SY041522
1H-Imidazole, 2,4,5-triphenyl-
SR-01000510787
SCHEMBL104130
Imidazole,4,5-triphenyl-
UNII-Q6K46G80ZD
cid_10232
2,4,5-Triphenyl-1H-imidazole #
EN300-1661101
TRIPHENDAZOLE
J-610082
2,4,5-Triphenyl-1H-imidazole
CCRIS 8668
IMIDAZOLE, 2,4,5-TRIPHENYL-
SR-01000510787-2
F1204-0058
AI3-50036
2,5-Triphenyl-1,3-imidazole
NSC 62790
AS-18377
484-47-9
HMS664I16
CS-W009969
Lophine
Lophin
NCI60_008969
1H-Imidazole,4,5-triphenyl-
ChemDiv1_027296

MDL Number

MFCD00005187

Customs Code

2933290090

FAQ

What are the physical and chemical properties of 2,4,5-Triphenyl-1H-imidazole (CAS: 484-47-9)?

2,4,5-Triphenyl-1H-imidazole is a crystalline solid with a molecular weight of approximately 357.34 g/mol. It has low water solubility and good solubility in organic solvents like chloroform and acetone. The compound is relatively stable under normal conditions but can react with strong acids and bases. It is used as a precursor in organic synthesis and as a building block in the synthesis of other heterocyclic compounds.

How is 2,4,5-Triphenyl-1H-imidazole (CAS: 484-47-9) typically synthesized?

2,4,5-Triphenyl-1H-imidazole is usually synthesized via the reaction of aniline derivatives with phthalimide under basic conditions. The synthesis involves the formation of an intermediate amide, which is then cyclized to form the imidazole ring. Catalysts such as sodium hydride are often used to improve the reaction yield and selectivity.

What industries use 2,4,5-Triphenyl-1H-imidazole (CAS: 484-47-9)?

2,4,5-Triphenyl-1H-imidazole is primarily used in the pharmaceutical industry as a precursor for the synthesis of various heterocyclic compounds with biological activity. It is also utilized in the semiconductor industry for the production of organic semiconductors and in the polymer industry for the development of conductive polymers.

What precautions should be taken when handling 2,4,5-Triphenyl-1H-imidazole (CAS: 484-47-9)?

When handling 2,4,5-Triphenyl-1H-imidazole, appropriate personal protective equipment (PPE) should be worn, including gloves, goggles, and a lab coat. The compound should be stored in a dry, cool place away from direct sunlight and heat sources. Fume hoods should be used during handling to minimize exposure. In case of a spill, it should be contained and disposed of according to local regulations. Safety data sheets (SDS) should be consulted for detailed information on handling and storage.