Compound Q&A

How is 2,4,5-Triphenyl-1H-imidazole (CAS: 484-47-9) typically synthesized?

Answer

2,4,5-Triphenyl-1H-imidazole
2,4,5-Triphenyl-1H-imidazole is usually synthesized via the reaction of aniline derivatives with phthalimide under basic conditions. The synthesis involves the formation of an intermediate amide, which is then cyclized to form the imidazole ring. Catalysts such as sodium hydride are often used to improve the reaction yield and selectivity.

About

CAS No 484-47-9
English Name 2,4,5-Triphenyl-1H-imidazole
Molecular Formula C21H16N2
Molecular Weight 296.37300000000005 g/mol
SMILES C1=CC=C(C=C1)C2=C(N=C(N2)C3=CC=CC=C3)C4=CC=CC=C4
InChIKey RNIPJYFZGXJSDD-UHFFFAOYSA-N
Last Updated: 2025-10-16 16:48

Related Q&A

Compound Q&A

What are the physical and chemical properties of 2,4,5-Triphenyl-1H-imidazole (CAS: 484-47-9)?

2,4,5-Triphenyl-1H-imidazole is a crystalline solid with a molecular weight of approximately 357.34 ...

Compound Q&A

What industries use 2,4,5-Triphenyl-1H-imidazole (CAS: 484-47-9)?

2,4,5-Triphenyl-1H-imidazole is primarily used in the pharmaceutical industry as a precursor for the...

Compound Q&A

What precautions should be taken when handling 2,4,5-Triphenyl-1H-imidazole (CAS: 484-47-9)?

When handling 2,4,5-Triphenyl-1H-imidazole, appropriate personal protective equipment (PPE) should b...

Compound Q&A

Are there alternatives to 1-(4-Chlorophenyl)-N-hydroxymethanimine (CAS: 3848-36-0) in synthesis?

When considering alternatives to 1-(4-Chlorophenyl)-N-hydroxymethanimine (CAS: 3...

3848-36-01-(4-Chlorophenyl)-N...
Compound Q&A

How is 3-(4-Bromophenyl)-5-(2-fluorophenyl)-1,2,4-oxadiazole (CAS: 419553-16-5) typically synthesized?

3-(4-Bromophenyl)-5-(2-fluorophenyl)-1,2,4-oxadiazole is synthesized through a m...

419553-16-53-(4-Bromophenyl)-5-...
Compound Q&A

How is 5-Chloro-2-(4-chlorophenyl)-4-methyl-6-[3-(1-piperidinyl)propoxy]pyrimidine (CAS: 1639220-19-1) typically synthesized?

5-Chloro-2-(4-chlorophenyl)-4-methyl-6-[3-(1-piperidinyl)propoxy]pyrimidine (CAS...

1639220-19-15-Chloro-2-(4-chloro...