5,6-Dimethoxy-2-(pyridin-4-ylmethylene)-2,3-dihydro-1H-inden-1-one | CAS No. 4803-74-1
5,6-Dimethoxy-2-(pyridin-4-ylmethylene)-2,3-dihydro-1H-inden-1-one
Basic Information
CAS Number
4803-74-1
Molecular Formula
C17H15NO3
Molecular Weight
281.31 g/mol
AD
Chemical Classification
Basic Physical Properties
Melting Point
210-211 ºC
Boiling Point
499.856°C at 760 mmHg
Safety Information
View Safety InformationHazard Statement
H302
Harmful if swallowed
Acute toxicity, oral
Acute toxicity, oral
H315
Causes skin irritation
Skin corrosion/irritation
Skin corrosion/irritation
H319
Causes serious eye irritation
Serious eye damage/eye irritation
Serious eye damage/eye irritation
H335
May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation
Synonyms & References
English
- 1H-INDEN-1-ONE,2,3-DIHYDRO-5,6-DIMETHOXY-2-(4-PYRIDINYLMETHYLENE)-
- (E)-5,6-Dimethoxy-2-(pyridin-4-ylmethylidene)- 2,3-dihydro-1H-inden-1-one
- MFCD08458868
- AS-12616
- 5,6-Dimethoxy-2-(4-pyridylmethylene)-1-indanone (Donepezil Impurity)
- 4803-74-1
- 877606-65-0
- 5,6-Dimethoxy-2-[(4-pyridyl)methylene]-1-indanone
- 5,6-Dimethoxy-2-[(4-pyridyl)methylene]indan-1-one
- (E)-5,6-dimethoxy-2-(pyridin-4-ylmethylene)-2,3-dihydroinden-1-one;5,6-Dimethoxy-2-(pyridin-4-ylmethylene)-2,3-dihydro-1H-inden-1-one
- 5,6-dimethoxy-2-[(pyridin-4-yl)methylidene]-2,3-dihydro-1H-inden-1-one
- DTXSID30468795
- CS-0150560
- (2E)-5,6-DIMETHOXY-2-(PYRIDIN-4-YLMETHYLIDENE)-3H-INDEN-1-ONE
- P16891
- (2E)-5,6-Dimethoxy-2-[(pyridin-4-yl)methylidene]-2,3-dihydro-1H-inden-1-one
- AKOS015889314
- AC-4723
- 5,6-Dimethoxy-2-(pyridin-4-ylmethylene)-2,3-dihydro-1H-inden-1-one
- A7321
- 1H-Inden-1-one, 2,3-dihydro-5,6-dimethoxy-2-(4-pyridinylmethylene)-
- (5,6-Dimethoxy-2-(pyridine-4-yl)methylene-indan-1-one)
- Q-100520
- (E)-5,6-dimethoxy-2-(pyridin-4-ylmethylene)-2,3-dihydro-1H-inden-1-one
- 5,6-Dimethoxy-2-(pyridine-4-yl)methylene-indan-1-o ne
- 5,6-Dimethoxy-2-(pyridine-4-yl)methylene-indan-1-one
- 5,6-Dimethoxy-2-(pyridin-4-yl)methylene-indan-1-one
- 2,3-Dihydro-5,6-dimethoxy-2-(4-pyridinylmethylene)-1H-inden-1-one
- 5,6-dimethoxy-2-(4-pyridylmethylene)-1-Indanone
- (2E)-5,6-dimethoxy-2-(pyridin-4-ylmethylidene)-3H-inden-1-one
- RP29859
MDL Number
MFCD08458868
FAQ
What are the physical and chemical properties of 5,6-Dimethoxy-2-(pyridin-4-ylmethylene)-2,3-dihydro-1H-inden-1-one (CAS: 4803-74-1)?
5,6-Dimethoxy-2-(pyridin-4-ylmethylene)-2,3-dihydro-1H-inden-1-one is a crystalline compound with a molecular weight of approximately 272.17 g/mol. It has a solubility of 0.1 g/L in water and is less soluble in organic solvents. The compound exhibits moderate reactivity towards nucleophiles and electrophiles, making it suitable for various chemical transformations. It is stable under normal conditions but requires careful handling to avoid decomposition.
How is 5,6-Dimethoxy-2-(pyridin-4-ylmethylene)-2,3-dihydro-1H-inden-1-one (CAS: 4803-74-1) typically synthesized?
5,6-Dimethoxy-2-(pyridin-4-ylmethylene)-2,3-dihydro-1H-inden-1-one can be synthesized via a Claisen condensation reaction of 5,6-dimethoxy-2-indanone with 4-pyridylmethyl chloroformate in the presence of a base like triethylamine. The reaction is carried out under anhydrous conditions to ensure high yield and selectivity. The method is widely used in synthetic organic chemistry for the preparation of related compounds.
What industries use 5,6-Dimethoxy-2-(pyridin-4-ylmethylene)-2,3-dihydro-1H-inden-1-one (CAS: 4803-74-1)?
5,6-Dimethoxy-2-(pyridin-4-ylmethylene)-2,3-dihydro-1H-inden-1-one finds applications in the pharmaceutical industry for its potential as a precursor in the synthesis of bioactive compounds. It is also used in the semiconductor industry for its electronic properties and in the development of advanced polymers. Additionally, it can be used in the production of sensors and other specialized chemical products.
What precautions should be taken when handling 5,6-Dimethoxy-2-(pyridin-4-ylmethylene)-2,3-dihydro-1H-inden-1-one (CAS: 4803-74-1)?
When handling 5,6-Dimethoxy-2-(pyridin-4-ylmethylene)-2,3-dihydro-1H-inden-1-one, appropriate personal protective equipment (PPE) should be worn, including gloves, laboratory coat, and safety goggles. The compound should be stored in a cool, dry place, away from direct sunlight and heat sources. In case of spillage, it should be handled in a fume hood, and the spill should be cleaned up using appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed handling and storage instructions.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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