Compound Q&A
How is 5,6-Dimethoxy-2-(pyridin-4-ylmethylene)-2,3-dihydro-1H-inden-1-one (CAS: 4803-74-1) typically synthesized?
Answer
5,6-Dimethoxy-2-(pyridin-4-ylmethylene)-2,3-dihydro-1H-inden-1-one can be synthesized via a Claisen condensation reaction of 5,6-dimethoxy-2-indanone with 4-pyridylmethyl chloroformate in the presence of a base like triethylamine. The reaction is carried out under anhydrous conditions to ensure high yield and selectivity. The method is widely used in synthetic organic chemistry for the preparation of related compounds.
About
CAS No
4803-74-1
English Name
5,6-Dimethoxy-2-(pyridin-4-ylmethylene)-2,3-dihydro-1H-inden-1-one
Molecular Formula
C17H15NO3
Molecular Weight
281.31 g/mol
SMILES
COC1=C(C=C2C(=C1)CC(=CC3=CC=NC=C3)C2=O)OC
InChIKey
SUVQWDLUAIFZKM-NTUHNPAUSA-N
Last Updated: 2025-09-26 00:09
