5,6-Dimethoxy-2-(pyridin-4-ylmethylene)-2,3-dihydro-1H-inden-1-one(CAS: 4803-74-1)

5,6-Dimethoxy-2-(pyridin-4-ylmethylene)-2,3-dihydro-1H-inden-1-one is a crystalline compound with a molecular weight of approximately 272.17 g/mol. It has a solubility of 0.1 g/L in water and is less soluble in organic solvents. The compound exhibits moderate reactivity towards nucleophiles and electrophiles, making it suitable for various chemical transformations. It is stable under normal conditions but requires careful handling to avoid decomposition.

5,6-Dimethoxy-2-(pyridin-4-ylmethylene)-2,3-dihydro-1H-inden-1-one can be synthesized via a Claisen condensation reaction of 5,6-dimethoxy-2-indanone with 4-pyridylmethyl chloroformate in the presence of a base like triethylamine. The reaction is carried out under anhydrous conditions to ensure high yield and selectivity. The method is widely used in synthetic organic chemistry for the preparation of related compounds.

5,6-Dimethoxy-2-(pyridin-4-ylmethylene)-2,3-dihydro-1H-inden-1-one finds applications in the pharmaceutical industry for its potential as a precursor in the synthesis of bioactive compounds. It is also used in the semiconductor industry for its electronic properties and in the development of advanced polymers. Additionally, it can be used in the production of sensors and other specialized chemical products.

When handling 5,6-Dimethoxy-2-(pyridin-4-ylmethylene)-2,3-dihydro-1H-inden-1-one, appropriate personal protective equipment (PPE) should be worn, including gloves, laboratory coat, and safety goggles. The compound should be stored in a cool, dry place, away from direct sunlight and heat sources. In case of spillage, it should be handled in a fume hood, and the spill should be cleaned up using appropriate absorbent materials. Always refer to the Safety Data Sheet (SDS) for detailed handling and storage instructions.