2,6-Dichloro-3-(tributylstannyl)pyrazine

Basic Information

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CAS Number

446285-70-7

Molecular Formula

C16H28Cl2N2Sn

Molecular Weight

438.03 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Agricultural Chemicals Pesticides Herbicides

Laboratory Chemicals Research Chemicals Biochemical Reagents

Basic Physical Properties

Solubility

Insuluble (7.0E-4 g/L) (25 ºC),

Refractive Index

n20/D 1.535

SMILES

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CCCC[Sn](CCCC)(CCCC)C1=NC=C(N=C1Cl)Cl

InChI

InChI=1S/C4HCl2N2.3C4H9.Sn/c5-3-1-7-2-4(6)8-3;3*1-3-4-2;/h1H;3*1,3-4H2,2H3;

InChIKey

IJOQAXKEUUCPAJ-UHFFFAOYSA-N

LogP

5.8395000000000055

Topological Polar Surface Area

25.78 Å²

Hydrogen Bond Donor/Acceptor

0 / 2

Complexity

257

Synonyms & References

English

2,6-DICHLORO-3-(TRIBUTYLSTANNYL)PYRAZINE
2,6-DICHLORO-3-(TRIBUTYLSTANNYL)PYRAZINE 0.96
3,5-Dichloro-2-(tributylstannyl)pyrazine
2,6-Dichloro-3-(tri-n-butylstannyl)pyrazine
tributyl-(3,5-dichloropyrazin-2-yl)stannane
2,6-Dichloro-3-(tri-N-butylstannyl)pyrazine,96%
DTXSID90376862
2,6-Dichloro-3-(tributylstannyl)pyrazine, 97%
2,6-Dichloro-3-(tributylstannyl)pyrazine
AKOS015843074
Tributyl-(3,5-dichloropyrazin-2-yl)stannane
CS-0088229
DB-105206
J-507415
WSA28570
3,5-dichloro-2-(tributylstannyl)pyrazine
SCHEMBL15561436
A872495
MFCD07787382
446285-70-7
C16H28Cl2N2Sn
SY318870

MDL Number

MFCD07787382

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 2,6-Dichloro-3-(tributylstannyl)pyrazine (CAS: 446285-70-7)?

2,6-Dichloro-3-(tributylstannyl)pyrazine is a solid with a crystalline form. It has a molecular weight of approximately 464.4 g/mol and is poorly soluble in water. This compound is known for its reactivity towards nucleophiles and its stability under normal conditions. It is a potential precursor in organometallic chemistry.

How is 2,6-Dichloro-3-(tributylstannyl)pyrazine (CAS: 446285-70-7) typically synthesized?

2,6-Dichloro-3-(tributylstannyl)pyrazine can be synthesized using a Grignard reaction followed by a Stille coupling. The reaction typically involves a pyrazine derivative, chlorides, and tributyltin chloride in the presence of a palladium catalyst. The yield is around 70-80%, with high selectivity towards the desired product.

What industries use 2,6-Dichloro-3-(tributylstannyl)pyrazine (CAS: 446285-70-7)?

2,6-Dichloro-3-(tributylstannyl)pyrazine is used in the pharmaceutical industry for the development of new drugs, particularly in the synthesis of complex organic molecules. It may also find applications in polymer chemistry and as a precursor in semiconductor materials.

What precautions should be taken when handling 2,6-Dichloro-3-(tributylstannyl)pyrazine (CAS: 446285-70-7)?

When handling 2,6-Dichloro-3-(tributylstannyl)pyrazine, it is essential to use personal protective equipment (PPE) such as gloves, goggles, and lab coat. Work should be performed in a well-ventilated fume hood to avoid inhalation. In case of spill, contact a chemical spill response team and refer to the Safety Data Sheet (SDS) for detailed instructions.