Compound Q&A

How is 2,6-Dichloro-3-(tributylstannyl)pyrazine (CAS: 446285-70-7) typically synthesized?

Answer

2,6-Dichloro-3-(tributylstannyl)pyrazine
2,6-Dichloro-3-(tributylstannyl)pyrazine can be synthesized using a Grignard reaction followed by a Stille coupling. The reaction typically involves a pyrazine derivative, chlorides, and tributyltin chloride in the presence of a palladium catalyst. The yield is around 70-80%, with high selectivity towards the desired product.

About

English Name 2,6-Dichloro-3-(tributylstannyl)pyrazine
Molecular Formula C16H28Cl2N2Sn
Molecular Weight 438.03 g/mol
SMILES CCCC[Sn](CCCC)(CCCC)C1=NC=C(N=C1Cl)Cl
InChIKey IJOQAXKEUUCPAJ-UHFFFAOYSA-N
Last Updated: 2025-12-28 10:59

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