p-Tolylmagnesium bromide

Basic Information

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CAS Number

4294-57-9

Molecular Formula

C7H7BrMg

Molecular Weight

195.34 g/mol

Chemical Classification

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

>300 ºC (acetonitrile ethyl ether )

Boiling Point

65-67 °C

SMILES

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CC1=CC=[C-]C=C1.[Mg+2].[Br-]

InChI

InChI=1S/C7H7.BrH.Mg/c1-7-5-3-2-4-6-7;;/h3-6H,1H3;1H;/q-1;;+2/p-1

InChIKey

BVUQKCCKUOSAEV-UHFFFAOYSA-M

LogP

2.64080

Complexity

129

Safety Information

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GHS Hazard Pictograms

H225

H314

H335

Hazard Statement

H225 Highly Flammable liquid and vapor
Flammable liquids

H314 Causes severe skin burns and eye damage
Skin corrosion/irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class 3/8 Class 3/8

Synonyms & References

English

DTXSID70884056
4-toluylmagnesium bromide
4-methylphenyl magnesium bromide
ZRJNGFJIBZKXTP-UHFFFAOYSA-M
4294-57-9
4-methylphenylmagnesiumbromide
p-Tolyl magnesium bromide
para-tolylmagnesium bromide
J-802284
MFCD00000040
4-methyl-phenylmagnesium bromide
4-tolylmagnesium bromide
bromo(4-methylphenyl)magnesium
p-methylphenylmagnesium bromide
p-tolyl-magnesium bromide
SCHEMBL232015
4-tolyl magnesium bromide
4-Methylphenylmagnesium bromide
4-Methylphenylmagnesium bromide 0.5 M in Tetrahydrofuran
Magnesium, bromo-p-tolyl-
AKOS015913055
4-Methylphenylmagnesium bromide, 1.0 M in 2-MeTHF
4-Tolylmagnesium bromide; Bromo(4-tolyl)magnesium; Bromo(p-methylphenyl)magnesium; Bromo-p-tolylmagnesium; T 1700
magnesium;methylbenzene;bromide
4-Methylphenylmagnesium bromide, 0.5 M in THF
p-Tolylmagnesium Bromide
Magnesium, bromo(4-methylphenyl)-
4-Methylphenylmagnesium bromide, 1.0M in 2-MeTHF
(P)-Tolylmagnesium bromide
magnesium,methylbenzene,bromide
N-(5-CHLORO-PYRIDIN-3-YL)-2,2-DIMETHYL-PROPIONAMIDE

MDL Number

MFCD00000040

Customs Code

2931900090

FAQ

What are the physical and chemical properties of p-Tolylmagnesium bromide (CAS: 4294-57-9)?

p-Tolylmagnesium bromide (CAS: 4294-57-9) is a white crystalline solid. It has a molecular weight of 167.23 g/mol and is soluble in organic solvents like ethanol and acetone. It is highly reactive and can undergo various nucleophilic substitution reactions.

How is p-Tolylmagnesium bromide (CAS: 4294-57-9) typically synthesized?

p-Tolylmagnesium bromide is typically synthesized by reacting p-tolylmagnesium chloride with sodium bromide in an ether solvent. The reaction is highly exothermic and requires careful temperature control.

What industries use p-Tolylmagnesium bromide (CAS: 4294-57-9)?

p-Tolylmagnesium bromide (CAS: 4294-57-9) is used in the pharmaceutical industry for the synthesis of various organic compounds, in organic synthesis for the preparation of heterocycles, and in the polymer industry for the modification of polymer structures.

What precautions should be taken when handling p-Tolylmagnesium bromide (CAS: 4294-57-9)?

When handling p-Tolylmagnesium bromide (CAS: 4294-57-9), use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Store it in a cool, dry place away from heat sources. Use a fume hood during synthesis and follow standard safety procedures as outlined in the material safety data sheet (MSDS/SDS).