Methyl diphenylphosphinite

Basic Information

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CAS Number

4020-99-9

Molecular Formula

C13H13OP

Molecular Weight

216.22 g/mol

Chemical Classification

Agricultural Chemicals Pesticides Insecticides

Basic Physical Properties

Boiling Point

149 °C/6 mmHg

Refractive Index

n20/D 1.604(lit.)

SMILES

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COP(C1=CC=CC=C1)C2=CC=CC=C2

InChI

InChI=1S/C13H13OP/c1-14-15(12-8-4-2-5-9-12)13-10-6-3-7-11-13/h2-11H,1H3

InChIKey

OAADXJFIBNEPLY-UHFFFAOYSA-N

LogP

2.6807000000000007

Topological Polar Surface Area

9.23 Å²

Hydrogen Bond Donor/Acceptor

0 / 1

Complexity

153

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class 6.1 Class 6.1

Sensitiveness

Air & Moisture Sensitive

Synonyms & References

English

EINECS 223-683-9
Methyl diphenylphosphinite
Diphenylphosphinous Acid Methyl Ester
methyldiphenyl phosphinite
F10242
Methoxydiphenylphosphine
methoxy(diphenyl)phosphane
NSC171167
AMY19756
DTXSID80193202
SY048353
CS-0085666
NSC 171167
MFCD00048025
NSC-171167
SCHEMBL187947
Phosphinous acid, diphenyl-, methyl ester
FT-0625275
Methyl diphenylphosphinite, 97%
A824980
D2557
NS00049258
4020-99-9
AKOS015905171
Diphenylmethoxyphosphine
methoxydiphenylphosphine
Diphenylphosphinous acid methyl ester
OAADXJFIBNEPLY-UHFFFAOYSA-N
PubChem6470
methoxydiphenylphosphane
OR10813

MDL Number

MFCD00048025

Customs Code

2909309090

FAQ

What are the physical and chemical properties of Methyl diphenylphosphinite (CAS: 4020-99-9)?

Methyl diphenylphosphinite (CAS: 4020-99-9) is a colorless or light yellow liquid with a molecular weight of approximately 228.27 g/mol. It has a specific gravity of 1.05 g/cm³ and a boiling point of 175°C. It is soluble in organic solvents like ethanol, methanol, and acetone. It is relatively stable in air but can react with water to form phosphoric acid. It is used in organophosphorus chemistry and as a precursor in the synthesis of organophosphorus compounds.

How is Methyl diphenylphosphinite (CAS: 4020-99-9) typically synthesized?

Methyl diphenylphosphinite can be synthesized by reacting phenylphosphine with methyl iodide in the presence of a base like sodium hydride. This reaction yields a high yield of the desired product with good selectivity. The reaction is conducted in an inert solvent like tetrahydrofuran (THF) at room temperature. Proper handling of the reagents and bases is necessary to ensure safety.

What industries use Methyl diphenylphosphinite (CAS: 4020-99-9)?

Methyl diphenylphosphinite (CAS: 4020-99-9) is primarily used in the pharmaceutical industry for the synthesis of drug candidates, in the polymer industry as a cross-linking agent, and in the semiconductor industry for the fabrication of organic light-emitting diodes (OLEDs). It is also utilized in the preparation of organophosphorus compounds for various applications including sensors and electronic devices.

What precautions should be taken when handling Methyl diphenylphosphinite (CAS: 4020-99-9)?

When handling Methyl diphenylphosphinite (CAS: 4020-99-9), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat. Work should be done in a fume hood to minimize inhalation risks. Spills should be cleaned up carefully using appropriate absorbents, and the area should be well-ventilated. Always refer to the safety data sheet (SDS) for detailed handling and storage instructions. This compound can react with water, so it is important to keep it dry and store it in a sealed container.