[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]acetonitrile | CAS No. 396131-82-1
[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]acetonitrile
Basic Information
CAS Number
396131-82-1
Molecular Formula
C14H18BNO2
Molecular Weight
243.11 g/mol
AD
Basic Physical Properties
Melting Point
44-48°C
Water Solubility
Slightly soluble in water.
Safety Information
View Safety InformationHazard Statement
Synonyms & References
English
- 3-(CYANOMETHYL)BENZENEBORONIC ACID PINACOL ESTER
- 3-(Cyanomethyl)phenylboronic acid, pinacol ester, AldrichCPR
- 2-[3-(tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]acetonitrile
- J-505704
- A824649
- SY025015
- 3-(cyanomethyl)benzeneboronic acid pinacol ester, AldrichCPR
- CS-0174450
- MFCD02179458
- BS-32392
- EN300-1852139
- SCHEMBL762075
- 396131-82-1
- LIWPKYSGWSFPEE-UHFFFAOYSA-N
- DTXSID40378391
- 2-(3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetonitrile
- AKOS015950758
- [3-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PHENYL]ACETONITRILE
- 3-Cyanomethylphenylboronic acid, pinacol ester
- 2-[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]acetonitrile
- 3-(Cyanomethyl)phenylboronic acid pinacol ester
- (3-Cyanomethyl)phenylboronic acid pinacol ester
- FT-0644572
- (3-CYANOMETHYLPHENYL)BORONIC ACID, PINACOL ESTER
- (3-(CYANOMETHYL)PHENYL)BORONIC ACID PINACOL ESTER
- (3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acetonitrile
- AB11170
- 3-(Cyanomethyl)Benzeneboronic Acid Pinacol Ester
- Benzeneacetonitrile,3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-
- 3-(Cyanomethyl)phenylboronic acid,pinacol ester
- [3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]acetonitrile
MDL Number
MFCD02179458
Customs Code
2931900090
FAQ
What are the physical and chemical properties of [3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]acetonitrile (CAS: 396131-82-1)?
[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]acetonitrile is a crystalline compound with a molecular weight of approximately 326.37 g/mol. It has a low solubility in water but is soluble in organic solvents. This compound is known for its reactivity in organoboron chemistry, particularly in Suzuki couplings. It is stable under normal conditions but should be kept away from strong oxidizers and heat.
How is [3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]acetonitrile (CAS: 396131-82-1) typically synthesized?
[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]acetonitrile is typically synthesized through a multistep process. The key step involves the reaction of phenylacetonitrile with 1,3,2-dioxaborine in the presence of a palladium catalyst and a base. The yield is generally around 70-80%, with good selectivity. This synthesis is commonly used in organoboron chemistry.
What industries use [3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]acetonitrile (CAS: 396131-82-1)?
[3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]acetonitrile is primarily used in the pharmaceutical and polymer industries. It serves as a key intermediate in the synthesis of organic compounds, particularly in the development of new drugs and the preparation of materials with specific properties. Its use in semiconductors and sensors is also growing due to its reactivity in organoboron chemistry.
What precautions should be taken when handling [3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]acetonitrile (CAS: 396131-82-1)?
Proper handling of [3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]acetonitrile (CAS: 396131-82-1) requires the use of personal protective equipment (PPE), including gloves, goggles, and a lab coat. It should be stored in a cool, dry place away from heat and strong oxidizers. In case of a spill, it should be handled with appropriate spill kits and proper disposal methods. Always refer to the Safety Data Sheet (SDS) for detailed handling and disposal information.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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