(2S)-2-[(2,2,2-Trichloroethoxy)carbonyl]-1-pyrrolidinecarboxylic acid | CAS No. 37888-34-9
(2S)-2-[(2,2,2-Trichloroethoxy)carbonyl]-1-pyrrolidinecarboxylic acid
Basic Information
CAS Number
37888-34-9
Molecular Formula
C8H10Cl3NO4
Molecular Weight
290.53 g/mol
AD
Chemical Classification
Basic Physical Properties
Synonyms & References
English
- 1,2-Pyrrolidinedicarboxylic acid, 1-(2,2,2-trichloroethyl) ester, (2S)-
- 1-[(2,2,2-TRICHLOROETHOXY)CARBONYL]PYRROLIDINE-2-CARBOXYLIC ACID
- ((2,2,2-Trichloroethoxy)carbonyl)-L-proline
- 1-[(2,2,2-Trichloroethoxy)carbonyl]proline
- A822375
- 1-(2,2,2-Trichloroethoxycarbonyl)-2-pyrrolidinecarboxylic acid
- 1-[oxo(2,2,2-trichloroethoxy)methyl]-2-pyrrolidinecarboxylic acid
- 1-[(2,2,2-TRICHLOROETHOXY)CARBONYL]-PYRROLIDINE-2-CARBOXYLIC ACID
- 1-[2,2,2-tris(chloranyl)ethoxycarbonyl]pyrrolidine-2-carboxylic acid
MDL Number
MFCD30531940
FAQ
What are the physical and chemical properties of (2S)-2-[(2,2,2-Trichloroethoxy)carbonyl]-1-pyrrolidinecarboxylic acid (CAS: 37888-34-9)?
(2S)-2-[(2,2,2-Trichloroethoxy)carbonyl]-1-pyrrolidinecarboxylic acid is a white crystalline powder with a molecular weight of 353.38 g/mol. It is slightly soluble in water and ethanol. This compound is reactive and can undergo esterification and amide formation. It is typically stored at room temperature away from moisture and light.
How is (2S)-2-[(2,2,2-Trichloroethoxy)carbonyl]-1-pyrrolidinecarboxylic acid (CAS: 37888-34-9) typically synthesized?
(2S)-2-[(2,2,2-Trichloroethoxy)carbonyl]-1-pyrrolidinecarboxylic acid is typically synthesized via the condensation of (2S)-2-hydroxy-1-pyrrolidinecarboxylic acid with trichloroethanol in the presence of a suitable coupling reagent like EDCl or HATU, followed by deprotection of the hydroxyl group to form the trichloroethoxycarbonyl derivative.
What industries use (2S)-2-[(2,2,2-Trichloroethoxy)carbonyl]-1-pyrrolidinecarboxylic acid (CAS: 37888-34-9)?
(2S)-2-[(2,2,2-Trichloroethoxy)carbonyl]-1-pyrrolidinecarboxylic acid is used in the pharmaceutical industry for the synthesis of various drugs, as well as in the polymer industry for modifying the properties of polymers. It is also utilized in the sensor and semiconductor industries for specific applications requiring its unique chemical properties.
What precautions should be taken when handling (2S)-2-[(2,2,2-Trichloroethoxy)carbonyl]-1-pyrrolidinecarboxylic acid (CAS: 37888-34-9)?
When handling (2S)-2-[(2,2,2-Trichloroethoxy)carbonyl]-1-pyrrolidinecarboxylic acid, appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn. It should be stored in a cool, dry place away from moisture and light. In case of a spill, it should be handled under a fume hood. For detailed safety information, refer to the Material Safety Data Sheet (MSDS/SDS).
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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