((2,2,2-TRICHLOROETHOXY)CARBONYL)-L-PROLINE(CAS: 37888-34-9)

(2S)-2-[(2,2,2-Trichloroethoxy)carbonyl]-1-pyrrolidinecarboxylic acid is a white crystalline powder with a molecular weight of 353.38 g/mol. It is slightly soluble in water and ethanol. This compound is reactive and can undergo esterification and amide formation. It is typically stored at room temperature away from moisture and light.

(2S)-2-[(2,2,2-Trichloroethoxy)carbonyl]-1-pyrrolidinecarboxylic acid is typically synthesized via the condensation of (2S)-2-hydroxy-1-pyrrolidinecarboxylic acid with trichloroethanol in the presence of a suitable coupling reagent like EDCl or HATU, followed by deprotection of the hydroxyl group to form the trichloroethoxycarbonyl derivative.

(2S)-2-[(2,2,2-Trichloroethoxy)carbonyl]-1-pyrrolidinecarboxylic acid is used in the pharmaceutical industry for the synthesis of various drugs, as well as in the polymer industry for modifying the properties of polymers. It is also utilized in the sensor and semiconductor industries for specific applications requiring its unique chemical properties.

When handling (2S)-2-[(2,2,2-Trichloroethoxy)carbonyl]-1-pyrrolidinecarboxylic acid, appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat should be worn. It should be stored in a cool, dry place away from moisture and light. In case of a spill, it should be handled under a fume hood. For detailed safety information, refer to the Material Safety Data Sheet (MSDS/SDS).