Compound Q&A
How is (2S)-2-[(2,2,2-Trichloroethoxy)carbonyl]-1-pyrrolidinecarboxylic acid (CAS: 37888-34-9) typically synthesized?
Answer
![(2S)-2-[(2,2,2-Trichloroethoxy)carbonyl]-1-pyrrolidinecarboxylic acid](https://static.chemtradehub.com/structs/378/37888-34-9-5e5f.webp "(2S)-2-[(2,2,2-Trichloroethoxy)carbonyl]-1-pyrrolidinecarboxylic acid")
(2S)-2-[(2,2,2-Trichloroethoxy)carbonyl]-1-pyrrolidinecarboxylic acid is typically synthesized via the condensation of (2S)-2-hydroxy-1-pyrrolidinecarboxylic acid with trichloroethanol in the presence of a suitable coupling reagent like EDCl or HATU, followed by deprotection of the hydroxyl group to form the trichloroethoxycarbonyl derivative.
About
CAS No
37888-34-9
English Name
(2S)-2-[(2,2,2-Trichloroethoxy)carbonyl]-1-pyrrolidinecarboxylic acid
Molecular Formula
C8H10Cl3NO4
Molecular Weight
290.53 g/mol
SMILES
OC(=O)N1CCC[C@H]1C(=O)OCC(Cl)(Cl)Cl
InChIKey
BSPWLSYOCMPUSC-YFKPBYRVSA-N
Last Updated: 2026-03-28 23:48
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