3-Pyrrolidinone hydrochloride (1:1)

Basic Information

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CAS Number

3760-52-9

Molecular Formula

C4H8ClNO

Molecular Weight

121.57 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Physical State

Yellow to Brown Solid

Melting Point

144-148°C

Boiling Point

197.8°C at 760 mmHg

SMILES

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C1CNCC1=O.Cl

InChI

InChI=1S/C4H7NO.ClH/c6-4-1-2-5-3-4;/h5H,1-3H2;1H

InChIKey

DPSTYIOIVSHZRI-UHFFFAOYSA-N

LogP

-0.029400000000000037

Topological Polar Surface Area

29.1 Å²

Hydrogen Bond Donor/Acceptor

1 / 2

Complexity

69.9

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

3-Pyrrolidone hydrochloride;3-Pyrrolidinone hydrochloride
SY019727
pyrrolidin-3-one;hydrochloride
3760-52-9
3-oxo-pyrrolidine hydrochloride
SCHEMBL969582
3-Pyrrolidinone HCl
3-Pyrrolidinone, hydrochloride
DPSTYIOIVSHZRI-UHFFFAOYSA-N
Pyrrolidin-3-one, HCl
BCP23231
Pyrrolidin-3-one--hydrogen chloride (1/1)
3-Pyrrolidinone hydrochloride, AldrichCPR
Z1741976513
3-Pyrrolidinone hydrochloride
AKOS005259351
EN300-173922
3-PYRROLIDONE HCL
3-Pyrrolidinonehydrochloride
CS-W005267
J-513103
DTXSID20598151
Pyrrolidin-3-one hydrochloride
SB10136
AC-22609
AM20120384
TS-01616
3-PYRROLIDINEONE HYDROCHLORIDE
A26594
FT-0647378
3-Pyrrolidinone hydrochloride;3-Pyrrolidinone HCl

MDL Number

MFCD02183811

Customs Code

2933990090

FAQ

What are the physical and chemical properties of 3-Pyrrolidinone hydrochloride (CAS: 3760-52-9)?

3-Pyrrolidinone hydrochloride (CAS: 3760-52-9) is a white crystalline powder with a molecular weight of approximately 162.67 g/mol. It has a solubility of about 40 g/L in water at 20°C. Chemically, it is moderately reactive and can form hydrogen bonds. It is slightly soluble in organic solvents like ethanol and acetone. It is commonly used in pharmaceuticals and as a precursor in organic synthesis.

How is 3-Pyrrolidinone hydrochloride (CAS: 3760-52-9) typically synthesized?

3-Pyrrolidinone hydrochloride (CAS: 3760-52-9) is typically synthesized by reacting 3-pyrrolidinone with hydrochloric acid. The reaction is conducted under mild conditions, often at room temperature, to avoid decomposition. The reaction is usually carried out in an aqueous medium with continuous stirring. The yield is typically over 90%, and the product is isolated by recrystallization from water.

What industries use 3-Pyrrolidinone hydrochloride (CAS: 3760-52-9)?

3-Pyrrolidinone hydrochloride (CAS: 3760-52-9) is widely used in the pharmaceutical industry for its solubilizing properties and as an intermediate in drug synthesis. It is also used in polymer science for the modification of polymer surfaces. Additionally, it finds applications in sensor technology and as a component in semiconductor fabrication processes.

What precautions should be taken when handling 3-Pyrrolidinone hydrochloride (CAS: 3760-52-9)?

When handling 3-Pyrrolidinone hydrochloride (CAS: 3760-52-9), it is essential to wear appropriate personal protective equipment (PPE) including gloves and safety glasses. Work should be conducted in a well-ventilated area or a fume hood to minimize exposure to the vapor. Spills should be cleaned up carefully, and proper disposal methods should be followed. Always refer to the safety data sheet (SDS) for detailed information on handling and storage.