Compound Q&A

How is 3-Pyrrolidinone hydrochloride (CAS: 3760-52-9) typically synthesized?

Answer

3-Pyrrolidinone hydrochloride (1:1)
3-Pyrrolidinone hydrochloride (CAS: 3760-52-9) is typically synthesized by reacting 3-pyrrolidinone with hydrochloric acid. The reaction is conducted under mild conditions, often at room temperature, to avoid decomposition. The reaction is usually carried out in an aqueous medium with continuous stirring. The yield is typically over 90%, and the product is isolated by recrystallization from water.

About

CAS No 3760-52-9
English Name 3-Pyrrolidinone hydrochloride (1:1)
Molecular Formula C4H8ClNO
Molecular Weight 121.57 g/mol
SMILES C1CNCC1=O.Cl
InChIKey DPSTYIOIVSHZRI-UHFFFAOYSA-N
Last Updated: 2025-09-09 19:18

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