4-Azidophenylalanine

Basic Information

View in Editor

CAS Number

33173-53-4

Molecular Formula

C9H10N4O2

Molecular Weight

206.2 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Nitriles

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Boiling Point

°Cat760mmHg

SMILES

View in Editor

c1cc(ccc1C[C@@H](C(=O)O)N)[N-][N+]#N

InChI

InChI=1S/C9H10N4O2/c10-8(9(14)15)5-6-1-3-7(4-2-6)12-13-11/h1-4,8H,5,10H2,(H,14,15)/t8-/m0/s1

InChIKey

NEMHIKRLROONTL-QMMMGPOBSA-N

LogP

1.73586

Complexity

267

Synonyms & References

English

L-Phenylalanine,4-azido-
(2S)-2-amino-3-(4-azidophenyl)propanoic acid
4-Azido-l-phenylalanine
H-4-Azido-Phe-OH
H-L-Phe(4-N3)-OH
H-P-AZIDO-PHE-OH
(S)-2-Amino-3-(4-azidophenyl)propanoic acid
4-Azidophenylalanine
L-Phenylalanine,4-azido
para-Azido-L-phenylalanine
p-Azido-L-phenylalanine
p-Azidophenylalanine
L-Phenylalanine, 4-azido-
4-Azido-D-phenylalanine
BCP18229
V5231
4-Azido-L-phenylalanine

MDL Number

MFCD00238100

Customs Code

2929909090

FAQ

What are the physical and chemical properties of 4-Azidophenylalanine (CAS: 33173-53-4)?

4-Azidophenylalanine is a crystalline compound with a molecular weight of approximately 252.11 g/mol. It has limited solubility in water but is more soluble in organic solvents. This compound reacts readily with nucleophiles due to the presence of the azido group. It shows good reactivity in both aqueous and organic media.

How is 4-Azidophenylalanine (CAS: 33173-53-4) typically synthesized?

4-Azidophenylalanine is typically synthesized by protecting the phenylalanine amine group, then introducing the azido group through a nucleophilic substitution reaction. Common methods include the use of sodium azide in the presence of an appropriate base. The reaction is selective and yields a high percentage of the desired product.

What industries use 4-Azidophenylalanine (CAS: 33173-53-4)?

4-Azidophenylalanine is used in various industries, including pharmaceuticals for drug development, where it serves as a building block for synthetic peptides. It is also used in polymer synthesis for creating functional materials, and in the development of sensors and semiconductors for electronic devices.

What precautions should be taken when handling 4-Azidophenylalanine (CAS: 33173-53-4)?

When handling 4-Azidophenylalanine, ensure to wear appropriate personal protective equipment (PPE), such as gloves and goggles. Work in a well-ventilated area or a fume hood to minimize inhalation risks. Store in a cool, dry place away from direct sunlight. In case of a spill, immediately clean up using appropriate absorbent materials and dispose of according to local regulations. Refer to the material safety data sheet (SDS) for detailed safety information.