4-Azidophenylalanine(CAS: 33173-53-4)

4-Azidophenylalanine is a crystalline compound with a molecular weight of approximately 252.11 g/mol. It has limited solubility in water but is more soluble in organic solvents. This compound reacts readily with nucleophiles due to the presence of the azido group. It shows good reactivity in both aqueous and organic media.

4-Azidophenylalanine is typically synthesized by protecting the phenylalanine amine group, then introducing the azido group through a nucleophilic substitution reaction. Common methods include the use of sodium azide in the presence of an appropriate base. The reaction is selective and yields a high percentage of the desired product.

4-Azidophenylalanine is used in various industries, including pharmaceuticals for drug development, where it serves as a building block for synthetic peptides. It is also used in polymer synthesis for creating functional materials, and in the development of sensors and semiconductors for electronic devices.

When handling 4-Azidophenylalanine, ensure to wear appropriate personal protective equipment (PPE), such as gloves and goggles. Work in a well-ventilated area or a fume hood to minimize inhalation risks. Store in a cool, dry place away from direct sunlight. In case of a spill, immediately clean up using appropriate absorbent materials and dispose of according to local regulations. Refer to the material safety data sheet (SDS) for detailed safety information.