4-((3-Chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylic acid | CAS No. 330786-34-0
4-((3-Chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylic acid
Basic Information
CAS Number
330786-34-0
Molecular Formula
C14H14ClN3O3S
Molecular Weight
339.8 g/mol
AD
Chemical Classification
Basic Physical Properties
Synonyms & References
English
- 5-Pyrimidinecarboxylic acid,4-[[(3-chloro-4-methoxyphenyl)methyl]amino]-2-(methylthio)-
- BS-50452
- PXYYGISXAWKTCT-UHFFFAOYSA-N
- 4-((3-Chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylicacid
- 4-((3-Chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylic acid
- A924332
- AVANAFIL IMPURITY 14
- 4-[(3-chloro-4-methoxyphenyl)methylamino]-2-methylsulfanylpyrimidine-5-carboxylic acid
- SCHEMBL4974720
- 330786-34-0
- SB57943
- CS-0150579
- 4-((3-chloro-4-methoxybenzyl)amino)-2-(methylthio) pyrimidine-5-carboxylic acid
- 4-{[(3-CHLORO-4-METHOXYPHENYL)METHYL]AMINO}-2-(METHYLSULFANYL)PYRIMIDINE-5-CARBOXYLIC ACID
- 2-methylthio-4-(3-chloro-4-methoxybenzylamino)-5-carboxypyrimidine
- 2-methylthio-4-(3-chloro-4-methoxybenzyl-amino)-5-carboxypyrimidine
MDL Number
MFCD28099353
FAQ
What are the physical and chemical properties of 4-((3-Chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylic acid (CAS: 330786-34-0)?
4-((3-Chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylic acid is a white crystalline solid at room temperature. Its molecular weight is approximately 414.13 g/mol. It is slightly soluble in water and more soluble in organic solvents. Chemically, it is an amine derivative of a pyrimidine carboxylic acid, which makes it reactive towards nucleophilic substitution reactions and condensation reactions.
How is 4-((3-Chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylic acid (CAS: 330786-34-0) typically synthesized?
This compound can be synthesized via a multistep process involving the condensation of an amino benzyl derivative with a chloro pyrimidine carboxylic acid followed by an alkylation step. The synthesis typically uses sodium hydride as a base and dimethyl sulfate as the alkylating agent. The yield is moderate, and the procedure involves careful handling of amines and haloarenes to ensure high purity and selectivity.
What industries use 4-((3-Chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylic acid (CAS: 330786-34-0)?
This compound has potential applications in the pharmaceutical industry as an intermediate in the synthesis of drug candidates. It is also explored for its role in polymer synthesis, where it can act as a functional monomer. Additionally, it may be used in the development of chemical sensors and in semiconductor technology, though its specific applications in these industries are less common.
What precautions should be taken when handling 4-((3-Chloro-4-methoxybenzyl)amino)-2-(methylthio)pyrimidine-5-carboxylic acid (CAS: 330786-34-0)?
Handling this compound requires appropriate Personal Protective Equipment (PPE), including gloves, goggles, and a lab coat. It should be stored in a well-ventilated area and away from sources of heat and ignition. If a spill occurs, it should be cleaned up carefully, and the area should be well-ventilated. Safety Data Sheets (SDS) should be consulted for detailed handling and disposal information. Ensure proper fume hood use during experimental procedures to minimize exposure risks.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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