3-Amino-3-(4-fluorophenyl)propanoic acid

Basic Information

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CAS Number

325-89-3

Molecular Formula

C9H10FNO2

Molecular Weight

183.18 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Physical State

White to Yellow Solid

Melting Point

216°C(dec.)

Boiling Point

308.8°Cat760mmHg

Density

1.289

Flash Point

140.6℃

Refractive Index

1.554

SMILES

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C1=CC(=CC=C1C(CC(=O)O)N)F

InChI

InChI=1S/C9H10FNO2/c10-7-3-1-6(2-4-7)8(11)5-9(12)13/h1-4,8H,5,11H2,(H,12,13)

InChIKey

CPGFMWPQXUXQRX-UHFFFAOYSA-N

LogP

1.3002

Topological Polar Surface Area

63.32000000000001 Å²

Hydrogen Bond Donor/Acceptor

3 / 3

Complexity

179

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

3-(4-Fluorophenyl)-beta-alanine
FT-0614947
FT-0630331
3-Amino-3-(4-fluorophenyl)propionic acid
3-amino-3-(4-fluorophenyl)propanoic acid
6R-0615
325-89-3
DTXSID20934373
AB16446
SY007326
BBL004561
AKOS016043239
3-Amino-3-(4-fluoro-phenyl)-propionic acid
EN300-05783
3-Amino-3-(4-fluorophenyl)propionic acid, 97%
BCP11675
CS-W017054
SR-01000597125-1
Z56921163
3-amino-3-(p-fluorophenyl)propionic acid
J-008864
AM20060940
h-d-beta-phe(4-f)-oh
rac-3-amino-3-(4-fluorophenyl)propanoic acid
dipentamethylenethiuramtetrasulfide
SCHEMBL1310948
MFCD00181811
J-502207
3-(4-Fluorophenyl)-beta-alanine #
dl-3-amino-3-(4-fluoro-phenyl)-propionic acid
Oprea1_786137

MDL Number

MFCD00181811

Customs Code

2922499990

FAQ

What are the physical and chemical properties of 3-Amino-3-(4-fluorophenyl)propanoic acid (CAS: 325-89-3)?

3-Amino-3-(4-fluorophenyl)propanoic acid is a crystalline solid with a molecular weight of approximately 210.17 g/mol. It has a low solubility in water but is soluble in organic solvents. This compound is moderately reactive, particularly towards nucleophilic substitution reactions and can form stable esters and amides. Its physical properties include a melting point of 165-167°C.

How is 3-Amino-3-(4-fluorophenyl)propanoic acid (CAS: 325-89-3) typically synthesized?

3-Amino-3-(4-fluorophenyl)propanoic acid is commonly synthesized via a multi-step process starting from 4-fluorophenyl acetic acid. The key steps involve fluorophenyl acetic acid reacting with an amino compound in the presence of a suitable catalyst, followed by purification and crystallization. The yield is generally around 80-85%, and the reaction is highly selective.

What industries use 3-Amino-3-(4-fluorophenyl)propanoic acid (CAS: 325-89-3)?

3-Amino-3-(4-fluorophenyl)propanoic acid is used in the pharmaceutical industry for the synthesis of certain drugs. It also finds applications in the polymer industry as a monomer for developing novel materials. Additionally, it is used in the semiconductor industry as a precursor in the fabrication of semiconductors and sensors.

What precautions should be taken when handling 3-Amino-3-(4-fluorophenyl)propanoic acid (CAS: 325-89-3)?

When handling 3-Amino-3-(4-fluorophenyl)propanoic acid, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. This compound should be stored in a cool, dry place away from sources of heat and ignition. In case of a spill, use appropriate absorbent materials and dispose of them according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed handling and safety information.