2-Amino-4-methoxyphenol hydrochloride (1:1)

Basic Information

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CAS Number

32190-97-9

Molecular Formula

C7H10ClNO2

Molecular Weight

175.62 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

SMILES

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COC1=CC(=C(C=C1)O)N.Cl

InChI

InChI=1S/C7H9NO2.ClH/c1-10-5-2-3-7(9)6(8)4-5;/h2-4,9H,8H2,1H3;1H

InChIKey

YWKXUUGVLZIYEG-UHFFFAOYSA-N

LogP

1.4047999999999998

Topological Polar Surface Area

55.480000000000004 Å²

Hydrogen Bond Donor/Acceptor

3 / 3

Complexity

108

Safety Information

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Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

2-Amino-4-methoxyphenolhydrochloride
2-amino-4-methoxyphenol;hydrochloride
BS-37771
CS-0323590
Phenol, 2-amino-4-methoxy-, hydrochloride (1:1)
SCHEMBL3020904
SFT7XQA9AN
YWKXUUGVLZIYEG-UHFFFAOYSA-N
EINECS 250-948-6
CHEMBL1502381
NS00060175
32190-97-9
Opera_ID_1251
MLS000716808
2-Amino-4-methoxyphenol hydrochloride
AKOS015847877
MFCD09997653
2-amino-4-(methyloxy)phenol HCl salt
SMR000278325
DTXSID40185966
Phenol, 2-amino-4-methoxy-, hydrochloride
2-AMINO-4-METHOXY-PHENOL HYDROCHLORIDE
2-Amino-4-methoxyphenol HCl
Phenol,2-amino-4-methoxy-, hydrochloride (1:1)

MDL Number

MFCD09997653

FAQ

What are the physical and chemical properties of 2-Amino-4-methoxyphenol hydrochloride (CAS: 32190-97-9)?

2-Amino-4-methoxyphenol hydrochloride (CAS: 32190-97-9) is a crystalline solid with a molecular weight of approximately 211.7 g/mol. It has a pKa of around 1.8, indicating it is a strong acid. The compound is slightly soluble in water and ethanol. It exhibits good solubility in organic solvents like dichloromethane and acetonitrile. Chemically, it is a hydroxy phenol derivative with aminomethoxy functionality, making it reactive towards nucleophiles and electrophiles.

How is 2-Amino-4-methoxyphenol hydrochloride (CAS: 32190-97-9) typically synthesized?

2-Amino-4-methoxyphenol hydrochloride is usually synthesized by the reaction of 4-methoxyphenol with hydrochloric acid or anhydrous hydrogen chloride. The synthesis involves the substitution of the hydroxyl group with a chloride ion, followed by the hydrolysis of the amino group to form the corresponding hydrochloride salt. Common solvents for this reaction include acetonitrile or dichloromethane. The reaction is typically carried out at room temperature with good yield and selectivity.

What industries use 2-Amino-4-methoxyphenol hydrochloride (CAS: 32190-97-9)?

2-Amino-4-methoxyphenol hydrochloride (CAS: 32190-97-9) is primarily used in the pharmaceutical industry as an intermediate in the synthesis of various drug candidates. It is also utilized in the polymer industry for the development of functional polymers with specific chemical properties. Additionally, it can be employed in the production of sensors and semiconductors due to its unique chemical reactivity and molecular structure.

What precautions should be taken when handling 2-Amino-4-methoxyphenol hydrochloride (CAS: 32190-97-9)?

When handling 2-Amino-4-methoxyphenol hydrochloride (CAS: 32190-97-9), it is essential to wear appropriate personal protective equipment (PPE), including gloves, goggles, and a lab coat. The compound should be stored in a sealed container in a cool, dry place away from direct sunlight. It should be handled in a well-ventilated area or in a fume hood due to its potential volatility and reactivity. In case of a spill, it should be handled according to the Material Safety Data Sheet (MSDS) guidelines, and the area should be thoroughly cleaned to prevent environmental contamination. Always refer to the latest MSDS for detailed safety information.