Compound Q&A

How is 2-Amino-4-methoxyphenol hydrochloride (CAS: 32190-97-9) typically synthesized?

Answer

2-Amino-4-methoxyphenol hydrochloride (1:1)
2-Amino-4-methoxyphenol hydrochloride is usually synthesized by the reaction of 4-methoxyphenol with hydrochloric acid or anhydrous hydrogen chloride. The synthesis involves the substitution of the hydroxyl group with a chloride ion, followed by the hydrolysis of the amino group to form the corresponding hydrochloride salt. Common solvents for this reaction include acetonitrile or dichloromethane. The reaction is typically carried out at room temperature with good yield and selectivity.

About

CAS No 32190-97-9
English Name 2-Amino-4-methoxyphenol hydrochloride (1:1)
Molecular Formula C7H10ClNO2
Molecular Weight 175.62 g/mol
SMILES COC1=CC(=C(C=C1)O)N.Cl
InChIKey YWKXUUGVLZIYEG-UHFFFAOYSA-N
Last Updated: 2026-03-22 19:38

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