5-Fluoro-2-benzofuran-1,3-dione

Basic Information

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CAS Number

319-03-9

Molecular Formula

C8H3FO3

Molecular Weight

166.11 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Specialty Chemicals UV Stabilizers

Agricultural Chemicals Pesticides Herbicides

Electronic Chemicals Semiconductor Materials Etchants

Basic Physical Properties

Melting Point

76.0 to 80.0 deg-C

Boiling Point

206°C/160mmHg

Flash Point

>93°C

Solubility

Soluble in sodium hydroxide.

Refractive Index

1.582

SMILES

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C1=CC2=C(C=C1F)C(=O)OC2=O

InChI

InChI=1S/C8H3FO3/c9-4-1-2-5-6(3-4)8(11)12-7(5)10/h1-3H

InChIKey

XVMKZAAFVWXIII-UHFFFAOYSA-N

LogP

1.1363

Topological Polar Surface Area

43.370000000000005 Å²

Hydrogen Bond Donor/Acceptor

0 / 3

Complexity

239

Safety Information

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GHS Hazard Pictograms

H301

H315

H319

H335

Hazard Statement

H301 Toxic if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Hazard Class

Class IRRITANT Class IRRITANT

Class MOISTURE SENSITIVE Class MOISTURE SENSITIVE

Sensitiveness

Moisture Sensitive

Synonyms & References

English

4-Fluorophthalic anhydride, 97%
DTXSID7059802
EN300-41346
J-517488
MFCD00191363
4-Fluorophthalic anhydride
4-fluorophthalic acid anhydride
319-03-9
AKOS005144306
5-Fluoro-isobenzofuran-1,3-dione
5-Fluoro-2-benzofuran-1,3-dione #
F0001-0954
4-fluorophthalicanhydride
5-Fluoroisobenzofuran-1,3-dione
5-FLUORO-1,3-DIHYDRO-2-BENZOFURAN-1,3-DIONE
NSC42091
5-Fluoro-2-benzofuran-1,3-dione
4fluorophthalic anhydride
J-018567
SY045297
NSC 42091
1,3-Isobenzofurandione, 5-fluoro-
SCHEMBL72124
F0322
BCP05918
4-fluorobenzene-1,2-dicarboxylic anhydride
HY-W015349
FT-0602301
CS-W016065
InChI=1/C8H3FO3/c9-4-1-2-5-6(3-4)8(11)12-7(5)10/h1-3
NS00126753

MDL Number

MFCD00191363

Customs Code

2932999099

FAQ

What are the physical and chemical properties of 5-Fluoro-2-benzofuran-1,3-dione (CAS: 319-03-9)?

5-Fluoro-2-benzofuran-1,3-dione is a crystalline solid with a molecular weight of approximately 219.07 g/mol. It has a low solubility in water but is more soluble in organic solvents like ethanol and acetone. Chemically, it is known for its stability but can react with bases and certain organic reagents. It is used in various chemical transformations due to its reactivity with nucleophiles.

How is 5-Fluoro-2-benzofuran-1,3-dione (CAS: 319-03-9) typically synthesized?

5-Fluoro-2-benzofuran-1,3-dione is typically synthesized via the oxidation of 5-fluoro-2-benzofuran using appropriate oxidizing agents like potassium permanganate or nitric acid. The reaction is carried out in aqueous media, and the yield is generally good, around 70-80%, with controlled selectivity to the desired product.

What industries use 5-Fluoro-2-benzofuran-1,3-dione (CAS: 319-03-9)?

5-Fluoro-2-benzofuran-1,3-dione is used in the pharmaceutical industry for the synthesis of certain drugs due to its pharmacological properties. It is also utilized in the polymer industry for improving the properties of certain polymers. Additionally, it finds applications in the production of semiconductors and in the development of chemical sensors.

What precautions should be taken when handling 5-Fluoro-2-benzofuran-1,3-dione (CAS: 319-03-9)?

When handling 5-Fluoro-2-benzofuran-1,3-dione, it is crucial to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted within a fume hood to minimize exposure. Spills should be handled carefully using appropriate absorbents, and the material safety data sheet (MSDS) should be consulted for detailed instructions. Storage should be in a cool, dry place away from direct sunlight and heat sources.