Methyl 2-amino-6-methylnicotinate

Basic Information

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CAS Number

31686-93-8

Molecular Formula

C8H10N2O2

Molecular Weight

166.18 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

SMILES

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CC1=NC(=C(C=C1)C(=O)OC)N

InChI

InChI=1S/C8H10N2O2/c1-5-3-4-6(7(9)10-5)8(11)12-2/h3-4H,1-2H3,(H2,9,10)

InChIKey

PUQVMSHLTBZBKX-UHFFFAOYSA-N

LogP

0.7588199999999998

Topological Polar Surface Area

65.21 Å²

Hydrogen Bond Donor/Acceptor

2 / 4

Complexity

172

Synonyms & References

English

2-amino-6-methyl-3-Pyridinecarboxylic acid methyl ester
2-amino-6-methylnicotinic acid methyl ester
methyl 2-amino-6-methyl-pyridine-3-carboxylate
SY060450
SB53736
2-Amino-6-methyl-nicotinic acid methyl ester
AKOS022637174
methyl 2-amino-6-methylpyridine-3-carboxylate
methyl2-amino-6-methylnicotinate
D82960
SCHEMBL1266209
CS-0161443
BS-16498
methyl 2-amino-6-methylnicotinate
EN300-179888
31686-93-8
MFCD16611580

MDL Number

MFCD16611580

FAQ

What are the physical and chemical properties of Methyl 2-amino-6-methylnicotinate (CAS: 31686-93-8)?

Methyl 2-amino-6-methylnicotinate (CAS: 31686-93-8) is a crystalline solid with a molecular weight of approximately 211.25 g/mol. It is slightly soluble in water and more soluble in organic solvents. Chemically, it exhibits amine and ester functionality, making it reactive towards both nucleophiles and electrophiles. It is stable under normal storage conditions but should be protected from strong oxidizing agents.

How is Methyl 2-amino-6-methylnicotinate (CAS: 31686-93-8) typically synthesized?

Methyl 2-amino-6-methylnicotinate is typically synthesized by the condensation of methyl 2-cyanonicotinate with methylamine in the presence of a base such as sodium hydroxide. The reaction is carried out in an aprotic solvent like dimethylformamide (DMF) under milder conditions compared to traditional methods, ensuring high yield and selectivity.

What industries use Methyl 2-amino-6-methylnicotinate (CAS: 31686-93-8)?

Methyl 2-amino-6-methylnicotinate (CAS: 31686-93-8) is used in the pharmaceutical industry for the synthesis of certain drugs. It is also utilized in the polymer industry as a stabilizer and in the electronics industry for applications in sensors and semiconductors due to its electronic properties.

What precautions should be taken when handling Methyl 2-amino-6-methylnicotinate (CAS: 31686-93-8)?

When handling Methyl 2-amino-6-methylnicotinate (CAS: 31686-93-8), appropriate safety precautions should be followed. Wear personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a well-ventilated area or a fume hood to avoid inhalation. Store the compound in a cool, dry place away from direct sunlight. In case of spill, clean up using appropriate spill control materials and follow the safety data sheet (SDS) for further guidance.