Compound Q&A
How is Methyl 2-amino-6-methylnicotinate (CAS: 31686-93-8) typically synthesized?
Answer
Methyl 2-amino-6-methylnicotinate is typically synthesized by the condensation of methyl 2-cyanonicotinate with methylamine in the presence of a base such as sodium hydroxide. The reaction is carried out in an aprotic solvent like dimethylformamide (DMF) under milder conditions compared to traditional methods, ensuring high yield and selectivity.
About
CAS No
31686-93-8
English Name
Methyl 2-amino-6-methylnicotinate
Molecular Formula
C8H10N2O2
Molecular Weight
166.18 g/mol
SMILES
CC1=NC(=C(C=C1)C(=O)OC)N
InChIKey
PUQVMSHLTBZBKX-UHFFFAOYSA-N
Last Updated: 2025-12-26 02:37
