Methyl 2-amino-6-methylnicotinate(CAS: 31686-93-8)

Methyl 2-amino-6-methylnicotinate (CAS: 31686-93-8) is a crystalline solid with a molecular weight of approximately 211.25 g/mol. It is slightly soluble in water and more soluble in organic solvents. Chemically, it exhibits amine and ester functionality, making it reactive towards both nucleophiles and electrophiles. It is stable under normal storage conditions but should be protected from strong oxidizing agents.

Methyl 2-amino-6-methylnicotinate is typically synthesized by the condensation of methyl 2-cyanonicotinate with methylamine in the presence of a base such as sodium hydroxide. The reaction is carried out in an aprotic solvent like dimethylformamide (DMF) under milder conditions compared to traditional methods, ensuring high yield and selectivity.

Methyl 2-amino-6-methylnicotinate (CAS: 31686-93-8) is used in the pharmaceutical industry for the synthesis of certain drugs. It is also utilized in the polymer industry as a stabilizer and in the electronics industry for applications in sensors and semiconductors due to its electronic properties.

When handling Methyl 2-amino-6-methylnicotinate (CAS: 31686-93-8), appropriate safety precautions should be followed. Wear personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work in a well-ventilated area or a fume hood to avoid inhalation. Store the compound in a cool, dry place away from direct sunlight. In case of spill, clean up using appropriate spill control materials and follow the safety data sheet (SDS) for further guidance.