Methyl 5-hydroxy-2-pyridinecarboxylate

Basic Information

View in Editor

CAS Number

30766-12-2

Molecular Formula

C7H7NO3

Molecular Weight

153.14 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Esters

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

193.5-195.5 ºC

SMILES

View in Editor

COC(=O)C1=NC=C(C=C1)O

InChI

InChI=1S/C7H7NO3/c1-11-7(10)6-3-2-5(9)4-8-6/h2-4,9H,1H3

InChIKey

YYAYXDDHGPXWTA-UHFFFAOYSA-N

LogP

0.5737999999999999

Topological Polar Surface Area

59.42 Å²

Hydrogen Bond Donor/Acceptor

1 / 4

Complexity

149

Synonyms & References

English

5-hydroxypicolinic acid methyl ester
5-Hydroxypyridine-2-carboxylic acid methyl ester
MFCD05256426
AS-5315
5-hydroxy picolinic acid methyl ester
30766-12-2
YYAYXDDHGPXWTA-UHFFFAOYSA-N
HY-W005963
methyl 5-hydroxypyridin-2-carboxylate
methyl-5-hydroxy-2-pyridinecarboxylate
SY021663
5-Hydroxy-pyridine-2-carboxylic acid methyl ester
AMY3705
J-522488
FT-0650322
EN300-316372
TD8012
Methyl 5-hydroxypicolinate
5-HYDROXY-2-PYRIDINECARBOXYLIC ACID METHYL ESTER
PB27686
DS-1589
methyl 5-hydroxypyridine-2-carboxylate
SCHEMBL164488
DTXSID80405832
CS-W005963
METHYL 5-HYDROXY-2-PYRIDINECARBOXYLATE
AKOS001476426
2-PYRIDINECARBOXYLIC ACID, 5-HYDROXY-, METHYL ESTER
5-hydroxy-pyridine-2-carboxylic acid methyl ester, AldrichCPR
AC-24316
Methyl5-hydroxypyridine-2-carboxylate

MDL Number

MFCD05256426

Customs Code

2933399090

FAQ

What are the physical and chemical properties of Methyl 5-hydroxy-2-pyridinecarboxylate (CAS: 30766-12-2)?

Methyl 5-hydroxy-2-pyridinecarboxylate (CAS: 30766-12-2) is a white crystalline solid with a molecular weight of approximately 176.17 g/mol. It has a solubility of about 12 g/L in water and is slightly soluble in common organic solvents such as ethanol and acetone. This compound is known for its reactivity, particularly in esterification and condensation reactions. It is stable under normal conditions but should be stored in a cool, dry place to prevent degradation.

How is Methyl 5-hydroxy-2-pyridinecarboxylate (CAS: 30766-12-2) typically synthesized?

Methyl 5-hydroxy-2-pyridinecarboxylate (CAS: 30766-12-2) is typically synthesized via an esterification reaction of 5-hydroxy-2-pyridinecarboxylic acid with methanol. Commonly, this is achieved using a strong acid catalyst like sulfuric acid or tosyl chloride. The reaction is conducted under mild conditions to ensure high selectivity and yield. The product can be purified by recrystallization from an appropriate solvent.

What industries use Methyl 5-hydroxy-2-pyridinecarboxylate (CAS: 30766-12-2)?

Methyl 5-hydroxy-2-pyridinecarboxylate (CAS: 30766-12-2) is primarily used in the pharmaceutical and chemical industries. It serves as a precursor for the synthesis of various organic compounds and has applications in the development of new drugs. Additionally, it is utilized in the production of some organic pigments and dyes. Due to its structural properties, it is also relevant in the field of polymer science for the development of specialized materials.

What precautions should be taken when handling Methyl 5-hydroxy-2-pyridinecarboxylate (CAS: 30766-12-2)?

When handling Methyl 5-hydroxy-2-pyridinecarboxylate (CAS: 30766-12-2), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. This compound should be stored in a cool, dry place away from direct sunlight. In case of a spill, it should be handled with care, and the area should be well-ventilated. Emergency spill kits should be readily available. A detailed safety data sheet (SDS) should be consulted for specific handling and disposal instructions.