Methyl 5-hydroxy-2-pyridinecarboxylate(CAS: 30766-12-2)

Methyl 5-hydroxy-2-pyridinecarboxylate (CAS: 30766-12-2) is a white crystalline solid with a molecular weight of approximately 176.17 g/mol. It has a solubility of about 12 g/L in water and is slightly soluble in common organic solvents such as ethanol and acetone. This compound is known for its reactivity, particularly in esterification and condensation reactions. It is stable under normal conditions but should be stored in a cool, dry place to prevent degradation.

Methyl 5-hydroxy-2-pyridinecarboxylate (CAS: 30766-12-2) is typically synthesized via an esterification reaction of 5-hydroxy-2-pyridinecarboxylic acid with methanol. Commonly, this is achieved using a strong acid catalyst like sulfuric acid or tosyl chloride. The reaction is conducted under mild conditions to ensure high selectivity and yield. The product can be purified by recrystallization from an appropriate solvent.

Methyl 5-hydroxy-2-pyridinecarboxylate (CAS: 30766-12-2) is primarily used in the pharmaceutical and chemical industries. It serves as a precursor for the synthesis of various organic compounds and has applications in the development of new drugs. Additionally, it is utilized in the production of some organic pigments and dyes. Due to its structural properties, it is also relevant in the field of polymer science for the development of specialized materials.

When handling Methyl 5-hydroxy-2-pyridinecarboxylate (CAS: 30766-12-2), it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. This compound should be stored in a cool, dry place away from direct sunlight. In case of a spill, it should be handled with care, and the area should be well-ventilated. Emergency spill kits should be readily available. A detailed safety data sheet (SDS) should be consulted for specific handling and disposal instructions.