2,6-Dichloro-9-(2,3,5-tri-O-acetyl-beta-D-ribofuranosyl)-9H-purine | CAS No. 3056-18-6
2,6-Dichloro-9-(2,3,5-tri-O-acetyl-beta-D-ribofuranosyl)-9H-purine
Basic Information
CAS Number
3056-18-6
Molecular Formula
C16H16Cl2N4O7
Molecular Weight
447.23 g/mol
AD
Chemical Classification
Basic Physical Properties
Melting Point
160-161 ºC
Boiling Point
555.3°C at 760 mmHg
Safety Information
View Safety InformationHazard Statement
H302
Harmful if swallowed
Acute toxicity, oral
Acute toxicity, oral
H315
Causes skin irritation
Skin corrosion/irritation
Skin corrosion/irritation
H319
Causes serious eye irritation
Serious eye damage/eye irritation
Serious eye damage/eye irritation
H335
May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation
Synonyms & References
English
- 2,6-dichloro-9-(2,3,5-tri-O-acetyl-beta-D-ribofuranosyl)-9H-purine
- 9-(2,3,5-tri-O-acetyl-beta-D-ribofuranosyl)-2,6-dichloropurine
- 2,6-Dichloro-9-(2 inverted exclamation mark ,3 inverted exclamation mark ,5 inverted exclamation mark -tri-O-acetyl-
- 2,6-Dichloro-9-(2',3',5'-tri-O-acetyl-beta-D-ribofuranosyl)purine
- 9-[2,3,5-Tri-O-acetyl-beta-D-ribofuranosyl]-2,6-dichloropurine
- 9-(2,3,5-tri- O-acetyl-beta-D-ribofuranosyl)-2,6-dichloro-9H-purine
- AKOS025392257
- (2R,3R,4R,5R)-4-(acetyloxy)-2-[(acetyloxy)methyl]-5-(2,6-dichloro-9H-purin-9-yl)tetrahydro-3-furanyl acetate
- MFCD02093101
- 3056-18-6
- 9-(2,3,5-tri-O-acetyl-beta-D-ribofuranosyl)-2,6-di-chloro-9H-purine
- D70543
- 2,6-Dichloro-9-(2,3,5-tri-O-acetyl-beta-D-ribofuranosyl)purine
- AS-2049
- (2R,3R,4R,5R)-2-(Acetoxymethyl)-5-(2,6-dichloro-9H-purin-9-yl)tetrahydrofuran-3,4-diyl diacetate
- 2,6-Dichloro-9-(2',3',5'-tri-O-acetyl-?-D-ribofuranosyl)purine
- 2,6-Dichloro-9-(2',3',5'-tri-O-acetyl-beta-D-ribofuranosyl)-9H-purine
- [(2R,3R,4R,5R)-3,4-bis(acetyloxy)-5-(2,6-dichloro-9H-purin-9-yl)oxolan-2-yl]methyl acetate
- C16H16Cl2N4O7
- 9H-Purine, 2,6-dichloro-9-(2,3,5-tri-O-acetyl-beta-D-ribofuranosyl)-
- 9-(2,3,5-tri-O-acetyl-beta-D-ribofuranosyl)-2,6-dichloro-9H-purine
- PYXZXWLFAMZVPY-SDBHATRESA-N
- SCHEMBL3770300
- A-D-ribofuranosyl)purine
- (2R,3R,4R,5R)-2-(Acetoxymethyl)-5-(2,6-dichloro-9H-purin-9-yl)tetrahydrofuran-3,4-diyldiacetate
- 2,6-Dichloro-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine
- 9H-Purine,2,6-dichloro-9-(2,3,5-tri-O-acetyl-b-D-ribofuranosyl)-
- 2,6-Dichloro-9-(2’,3’,5’-tri-O-acetyl-β-D-ribofuranosyl)purine
- [(2R,3R,4R,5R)-3,4-diacetyloxy-5-(2,6-dichloropurin-9-yl)oxolan-2-yl]methyl acetate
- [3,4-Bis(acetyloxy)-5-(2,6-dichloro-9H-purin-9-yl)oxolan-2-yl]methyl acetate
- 2,6-DICHLORO-9-(2’,3’,5’-TRI-O-ACETYL-B-D-RIBOFURANOSYL)PURINE
MDL Number
MFCD02093101
Customs Code
2934999090
FAQ
What are the physical and chemical properties of 2,6-Dichloro-9-(2,3,5-tri-O-acetyl-beta-D-ribofuranosyl)-9H-purine (CAS: 3056-18-6)?
2,6-Dichloro-9-(2,3,5-tri-O-acetyl-beta-D-ribofuranosyl)-9H-purine is a crystalline compound with a molecular weight of approximately 606.03 g/mol. It is poorly soluble in water but soluble in organic solvents. The compound is stable but may react with strong bases. It is not flammable under usual conditions.
How is 2,6-Dichloro-9-(2,3,5-tri-O-acetyl-beta-D-ribofuranosyl)-9H-purine (CAS: 3056-18-6) typically synthesized?
2,6-Dichloro-9-(2,3,5-tri-O-acetyl-beta-D-ribofuranosyl)-9H-purine is synthesized through the acetylation of 2,6-dichloropurine followed by the coupling with 2,3,5-tri-O-acetyl-D-ribofuranose. Common catalysts include acetic anhydride and reagents such as HATU in the presence of a base like DIPEA. The yield is typically around 70-80%.
What industries use 2,6-Dichloro-9-(2,3,5-tri-O-acetyl-beta-D-ribofuranosyl)-9H-purine (CAS: 3056-18-6)?
2,6-Dichloro-9-(2,3,5-tri-O-acetyl-beta-D-ribofuranosyl)-9H-purine is primarily used in the pharmaceutical industry for the synthesis of nucleoside analogs. It also finds applications in the development of certain types of sensors and as a precursor in organic synthesis for the production of other biologically active compounds.
What precautions should be taken when handling 2,6-Dichloro-9-(2,3,5-tri-O-acetyl-beta-D-ribofuranosyl)-9H-purine (CAS: 3056-18-6)?
When handling 2,6-Dichloro-9-(2,3,5-tri-O-acetyl-beta-D-ribofuranosyl)-9H-purine, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up immediately and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed information.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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