2,6-Dichloro-9-(2,3,5-tri-O-acetyl-beta-D-ribofuranosyl)-9H-purine(CAS: 3056-18-6)

2,6-Dichloro-9-(2,3,5-tri-O-acetyl-beta-D-ribofuranosyl)-9H-purine is a crystalline compound with a molecular weight of approximately 606.03 g/mol. It is poorly soluble in water but soluble in organic solvents. The compound is stable but may react with strong bases. It is not flammable under usual conditions.

2,6-Dichloro-9-(2,3,5-tri-O-acetyl-beta-D-ribofuranosyl)-9H-purine is synthesized through the acetylation of 2,6-dichloropurine followed by the coupling with 2,3,5-tri-O-acetyl-D-ribofuranose. Common catalysts include acetic anhydride and reagents such as HATU in the presence of a base like DIPEA. The yield is typically around 70-80%.

2,6-Dichloro-9-(2,3,5-tri-O-acetyl-beta-D-ribofuranosyl)-9H-purine is primarily used in the pharmaceutical industry for the synthesis of nucleoside analogs. It also finds applications in the development of certain types of sensors and as a precursor in organic synthesis for the production of other biologically active compounds.

When handling 2,6-Dichloro-9-(2,3,5-tri-O-acetyl-beta-D-ribofuranosyl)-9H-purine, it is important to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. Work should be conducted in a well-ventilated area or a fume hood. Spills should be cleaned up immediately and disposed of according to local regulations. Always refer to the Safety Data Sheet (SDS) for detailed information.