Compound Q&A
How is 2,6-Dichloro-9-(2,3,5-tri-O-acetyl-beta-D-ribofuranosyl)-9H-purine (CAS: 3056-18-6) typically synthesized?
Answer
2,6-Dichloro-9-(2,3,5-tri-O-acetyl-beta-D-ribofuranosyl)-9H-purine is synthesized through the acetylation of 2,6-dichloropurine followed by the coupling with 2,3,5-tri-O-acetyl-D-ribofuranose. Common catalysts include acetic anhydride and reagents such as HATU in the presence of a base like DIPEA. The yield is typically around 70-80%.
About
CAS No
3056-18-6
English Name
2,6-Dichloro-9-(2,3,5-tri-O-acetyl-beta-D-ribofuranosyl)-9H-purine
Molecular Formula
C16H16Cl2N4O7
Molecular Weight
447.23 g/mol
SMILES
CC(=O)OCC1C(C(C(O1)N2C=NC3=C2N=C(N=C3Cl)Cl)OC(=O)C)OC(=O)C
InChIKey
PYXZXWLFAMZVPY-SDBHATRESA-N
Last Updated: 2025-12-29 01:16
