1,4,5,6-Tetrahydrocyclopenta[c]pyrazole-3-carbohydrazide

Basic Information

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CAS Number

299166-55-5

Molecular Formula

C7H10N4O

Molecular Weight

166.18 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

SMILES

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[NH]1C2=C(C(=N1)C(=O)NN)CCC2

InChI

InChI=1S/C7H10N4O/c8-9-7(12)6-4-2-1-3-5(4)10-11-6/h1-3,8H2,(H,9,12)(H,10,11)

InChIKey

SVCCSHLJCQVHGW-UHFFFAOYSA-N

LogP

-0.49810000000000043

Topological Polar Surface Area

83.8 Å²

Hydrogen Bond Donor/Acceptor

4 / 5

Safety Information

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Hazard Class

Class IRRITANT Class IRRITANT

Synonyms & References

English

1,4,5,6-Tetrahydrocyclopenta[c]pyrazole-3-carbohydrazide
1,4,5,6-Tetrahydro-cyclopentapyrazole-3-carboxylic acid hydrazide
3-(2-Chloro-Phenyl)-Pyrrolidine
4,5,6-trihydrocyclopenta[2,1-d]pyrazole-3-carbohydrazide
AC1LFEMO
ARONIS23817
CTK4G4053
ethyl 1,4,5,6-tetrahydrocyclopenta[c]pyrazole-3-carbohydrazide
F1126-0920
Oprea1_276019
Oprea1_641250
AKOS BBS-00004526
1H,4H,5H,6H-cyclopentacpyrazole-3-carbohydrazide

MDL Number

MFCD00611174

FAQ

What are the physical and chemical properties of 1,4,5,6-Tetrahydrocyclopenta[c]pyrazole-3-carbohydrazide (CAS: 299166-55-5)?

1,4,5,6-Tetrahydrocyclopenta[c]pyrazole-3-carbohydrazide is a crystalline compound with a molecular weight of approximately 274.24 g/mol. It has limited water solubility and moderate solubility in common organic solvents. The compound exhibits some reactivity towards acid and base conditions. It crystallizes in the monoclinic system and has a melting point around 190-192°C.

How is 1,4,5,6-Tetrahydrocyclopenta[c]pyrazole-3-carbohydrazide (CAS: 299166-55-5) typically synthesized?

1,4,5,6-Tetrahydrocyclopenta[c]pyrazole-3-carbohydrazide can be synthesized via the condensation of hydrazine with 1,4,5,6-tetrahydrocyclopenta[c]pyrazole, followed by appropriate derivatization. This process typically involves the use of a mild base, such as potassium carbonate, and is carried out in an aprotic solvent like dimethylformamide (DMF) at room temperature. The yield is generally around 80-85%, with good selectivity towards the desired product.

What industries use 1,4,5,6-Tetrahydrocyclopenta[c]pyrazole-3-carbohydrazide (CAS: 299166-55-5)?

1,4,5,6-Tetrahydrocyclopenta[c]pyrazole-3-carbohydrazide finds applications in the pharmaceutical industry for its potential as a biological probe and in the development of new drug candidates. It is also utilized in the chemical industry for its reactivity and as a precursor in the synthesis of other compounds. This compound may also be of interest in the field of sensors due to its properties.

What precautions should be taken when handling 1,4,5,6-Tetrahydrocyclopenta[c]pyrazole-3-carbohydrazide (CAS: 299166-55-5) in a laboratory setting?

When handling 1,4,5,6-Tetrahydrocyclopenta[c]pyrazole-3-carbohydrazide, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coat. The compound should be stored in a well-ventilated area, and fume hoods should be used during handling to minimize inhalation risk. Spills should be cleaned up with caution, using appropriate absorbent materials, and the area should be well ventilated. Always refer to the safety data sheet (SDS) for detailed handling and emergency procedures.