1,4,5,6-Tetrahydrocyclopenta[c]pyrazole-3-carbohydrazide(CAS: 299166-55-5)

1,4,5,6-Tetrahydrocyclopenta[c]pyrazole-3-carbohydrazide is a crystalline compound with a molecular weight of approximately 274.24 g/mol. It has limited water solubility and moderate solubility in common organic solvents. The compound exhibits some reactivity towards acid and base conditions. It crystallizes in the monoclinic system and has a melting point around 190-192°C.

1,4,5,6-Tetrahydrocyclopenta[c]pyrazole-3-carbohydrazide can be synthesized via the condensation of hydrazine with 1,4,5,6-tetrahydrocyclopenta[c]pyrazole, followed by appropriate derivatization. This process typically involves the use of a mild base, such as potassium carbonate, and is carried out in an aprotic solvent like dimethylformamide (DMF) at room temperature. The yield is generally around 80-85%, with good selectivity towards the desired product.

1,4,5,6-Tetrahydrocyclopenta[c]pyrazole-3-carbohydrazide finds applications in the pharmaceutical industry for its potential as a biological probe and in the development of new drug candidates. It is also utilized in the chemical industry for its reactivity and as a precursor in the synthesis of other compounds. This compound may also be of interest in the field of sensors due to its properties.

When handling 1,4,5,6-Tetrahydrocyclopenta[c]pyrazole-3-carbohydrazide, it is essential to wear appropriate personal protective equipment (PPE) such as gloves, goggles, and lab coat. The compound should be stored in a well-ventilated area, and fume hoods should be used during handling to minimize inhalation risk. Spills should be cleaned up with caution, using appropriate absorbent materials, and the area should be well ventilated. Always refer to the safety data sheet (SDS) for detailed handling and emergency procedures.