5H-Dibenzo[b,f]azepine-5-carboxamide

Basic Information

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CAS Number

298-46-4

Molecular Formula

C15H12N2O

Molecular Weight

236.27 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Basic Physical Properties

Melting Point

191-192 °C

Boiling Point

411°C at 760 mmHg

Flash Point

202.4℃

Solubility

45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: soluble29mg/mL

Refractive Index

1.5906 (estimate)

SMILES

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NC(=O)N1c2ccccc2C=Cc3ccccc13

InChI

InChI=1S/C15H12N2O/c16-15(18)17-13-7-3-1-5-11(13)9-10-12-6-2-4-8-14(12)17/h1-10H,(H2,16,18)

InChIKey

FFGPTBGBLSHEPO-UHFFFAOYSA-N

LogP

3.3872000000000018

Topological Polar Surface Area

46.330000000000005 Å²

Hydrogen Bond Donor/Acceptor

2 / 3

Complexity

326

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H317 May cause an allergic skin reaction
Sensitization, Skin

H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled
Sensitization, respiratory

Toxicity

LD50 orally in mice, rats: 3750, 4025 mg/kg (Stenger, Roulet)

Synonyms & References

English

5H-Dibenzo[b,f]azepine-5-carboxamide
CARBAMAZEPIN
CARBAMAZEPINE
ANBROMINE
TEGRETOL
5-Carbamoyl-5H-dibenzo(b,f)azepine
5-Carbamoyldibenzo(b,f)azepine
Carbamazepine Solution
5H-Dibenz[b,f]azepine-5-carboxamide
Biston
Calepsin
Carbelan
CBZ
Epitol
Lexin
Neurotol
NSC 169864
Sirtal
Timonil
5-Carbamoyl-5H-dibenz[b,f]azepine
Carbamazepen
Finlepsin
Carbazepine
Equetro
Carbamezepine
Tegretal
Carbatrol
Karbamazepin
Telesmin
Stazepine
Tegretol-Xr

MDL Number

MFCD00005073

Customs Code

2933990090

FAQ

What is 5H-Dibenzo[b,f]azepine-5-carboxamide (CAS: 298-46-4)?

5H-Dibenzo[b,f]azepine-5-carboxamide (CAS: 298-46-4) is a heterocyclic organic compound containing a dibenzoazepine ring system with a carboxamide functional group. It is known for its stability and is commonly used in chemical research and pharmaceutical development. Its molecular formula is C17H14N2O2, and it typically appears as a white crystalline solid with a melting point around 240-242°C.

What are the main uses of 5H-Dibenzo[b,f]azepine-5-carboxamide (CAS: 298-46-4)?

5H-Dibenzo[b,f]azepine-5-carboxamide (CAS: 298-46-4) is primarily used in pharmaceutical research for the development of drugs targeting neurological disorders. It also serves as an intermediate in the synthesis of various organic compounds and is studied for its potential applications in medicinal chemistry and material science. Its unique structure makes it valuable in drug design and chemical synthesis processes.

Is 5H-Dibenzo[b,f]azepine-5-carboxamide (CAS: 298-46-4) safe?

5H-Dibenzo[b,f]azepine-5-carboxamide (CAS: 298-46-4) is generally considered safe when handled properly. However, it should be treated with caution as it may cause irritation to the skin, eyes, or respiratory system. Protective gloves, goggles, and a well-ventilated workspace are recommended. Always follow safety guidelines and regulations for handling chemical compounds, especially those with potential toxicity.

How should 5H-Dibenzo[b,f]azepine-5-carboxamide (CAS: 298-46-4) be stored?

5H-Dibenzo[b,f]azepine-5-carboxamide (CAS: 298-46-4) should be stored in a cool, dry, and dark place away from moisture and strong light. It is typically kept in a sealed container at a temperature below 25°C. Ensure proper ventilation and avoid exposure to incompatible materials to maintain stability and prevent degradation.