2-amino-3-(4-nitrophenyl)propanoic acid

Basic Information

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CAS Number

2922-40-9

Molecular Formula

C9H10N2O4

Molecular Weight

210.19 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Fine Chemicals Dyes and Pigments Organic Dyes

Basic Physical Properties

Melting Point

236-237 °C (dec.)

Density

1.4080

SMILES

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C1=CC(=CC=C1CC(C(=O)O)N)[N+](=O)[O-]

InChI

InChI=1S/C9H10N2O4/c10-8(9(12)13)5-6-1-3-7(4-2-6)11(14)15/h1-4,8H,5,10H2,(H,12,13)

InChIKey

GTVVZTAFGPQSPC-UHFFFAOYSA-N

LogP

1.77270

Complexity

243

Safety Information

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GHS Hazard Pictograms

H301

Hazard Statement

H301 Toxic if swallowed
Acute toxicity, oral

Synonyms & References

English

FT-0627632
p-Nitro-dl-phenylalanine
CHEBI:48496
4-Nitro-DL-phenylalanine (H-DL-Phe(4-NO2)-OH)
4-nitro-d,l-phenylalanine
4-Nitrophenylalanine
H-DL-Phe(4-NO2)-OH
Phenylalanine, 4-nitro-
AI3-52611
dl-p-Nitrophenylalanine
4-Nitro-DL-phenylalanine
DL-Phenylalanine, 4-nitro-
NSC 14786
NSC 148865
WLN: WNR D1YZVQ
WLN: WNR D1YZVQ -L
4-Nitrophenylalanine #
L-.beta.-Nitrophenylalanine
J-017441
NSC152925
NSC-152925
2-amino-3-(4-nitrophenyl)propanoic acid
H-p-Nitro-DL-Phe-OH
NCGC00253665-01
EN300-123066
N0952
2922-40-9
AS-38157
p-Nitrophenylalanine, DL-
EINECS 220-868-6
NSC-148865

MDL Number

MFCD00007384

FAQ

What are the physical and chemical properties of 2-amino-3-(4-nitrophenyl)propanoic acid (CAS: 2922-40-9)?

2-Amino-3-(4-nitrophenyl)propanoic acid (CAS: 2922-40-9) is a crystalline solid with a molecular weight of approximately 225.11 g/mol. It has a pKa of around 4.2 and is slightly soluble in water. This compound is reactive towards nucleophiles and can undergo substitution reactions. It has a low vapor pressure and is stable under normal conditions.

How is 2-amino-3-(4-nitrophenyl)propanoic acid (CAS: 2922-40-9) typically synthesized?

2-Amino-3-(4-nitrophenyl)propanoic acid (CAS: 2922-40-9) is commonly synthesized via the coupling of 4-nitrophenyl chloroformate with 2-amino-3-hydroxypropanoic acid. The reaction typically occurs in the presence of a base such as diisopropylethylamine. The yield is generally around 70-80%, and the product is purified by recrystallization.

What industries use 2-amino-3-(4-nitrophenyl)propanoic acid (CAS: 2922-40-9)?

2-Amino-3-(4-nitrophenyl)propanoic acid (CAS: 2922-40-9) is used in the pharmaceutical industry for the synthesis of certain drugs. It is also utilized in the production of sensors and in some polymer formulations for its specific functional groups. However, its specific applications are limited due to its chemical reactivity.

What precautions should be taken when handling 2-amino-3-(4-nitrophenyl)propanoic acid (CAS: 2922-40-9)?

When handling 2-amino-3-(4-nitrophenyl)propanoic acid (CAS: 2922-40-9), it is essential to use appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat. The compound should be handled in a well-ventilated area or a fume hood. In case of a spill, wipe up with absorbent material and dispose of according to safety guidelines. Refer to the Safety Data Sheet (SDS) for detailed information.