2-Chloro-3-nitro-4-pyridinamine

Basic Information

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CAS Number

2789-25-5

Molecular Formula

C5H4ClN3O2

Molecular Weight

173.56 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Amines

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Agricultural Chemicals Pesticides Herbicides

Water Treatment Chemicals Coagulants and Flocculants Inorganic Coagulants

Basic Physical Properties

Physical State

Solid

Melting Point

198-204°C

Boiling Point

392.8℃ at 760 mmHg

Density

1.596

Flash Point

191.4 °C

SMILES

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C1=CN=C(C(=C1N)[N+](=O)[O-])Cl

InChI

InChI=1S/C5H4ClN3O2/c6-5-4(9(10)11)3(7)1-2-8-5/h1-2H,(H2,7,8)

InChIKey

PDQAWJXOYURKPI-UHFFFAOYSA-N

LogP

2.32980

Complexity

160

Safety Information

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Hazard Statement

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

Sensitiveness

对空气敏感

Synonyms & References

English

J-508680
AB32151
MFCD07368898
CL0270
FT-0649199
EN300-217471
2789-25-5
SCHEMBL203785
2-chloro-3-nitro-4-aminopyridine
4-Amino-2-chloro-3-nitropyridine
PS-3887
4-PYRIDINAMINE, 2-CHLORO-3-NITRO-
2-chloro-3-nitro-pyridin-4-amine
PDQAWJXOYURKPI-UHFFFAOYSA-N
AM803626
AC-2407
2-Chloro-3-nitropyridin-4-amine
4-Pyridinamine,2-chloro-3-nitro-
AKOS006343544
2-chloro-3-nitropyridin-4-amine;4-Amino-2-chloro-3-nitropyridine
SY020357
DTXSID90450015
CS-D0718
2-CHLORO-3-NITRO-4-PYRIDINAMINE
4-amino-2-chloro-3-nitropyridine, AldrichCPR
2-CHLORO-3-NITROPYRIDIN-4-AMINE
2-Chloro-4-amino-3-nitropyridine
4-Amino-2-chloro-3-nitro-pyridine
2-chloro-3-nitro
2-Chloro-3-nitro-4-aminopyridine
2-Chloro-3-nitro-4-pyridinamine

MDL Number

MFCD07368898

Customs Code

2933399090

FAQ

What are the physical and chemical properties of 2-Chloro-3-nitro-4-pyridinamine (CAS: 2789-25-5)?

2-Chloro-3-nitro-4-pyridinamine is a crystalline solid with a molecular weight of approximately 207.58 g/mol. It has low water solubility and is moderately soluble in polar solvents like dimethylformamide. It reacts readily with reducing agents and can undergo nitro reduction under controlled conditions. This compound has a melting point of about 145-147°C and is stable under normal laboratory conditions.

How is 2-Chloro-3-nitro-4-pyridinamine (CAS: 2789-25-5) typically synthesized?

2-Chloro-3-nitro-4-pyridinamine is commonly synthesized via the nitration of 2-chloro-4-pyridinamine and subsequent purification. The nitration step typically involves the use of concentrated nitric acid and sulfuric acid as the nitrating mixture. The reaction is conducted in a fume hood under controlled temperature conditions to ensure safety and high yield.

What industries use 2-Chloro-3-nitro-4-pyridinamine (CAS: 2789-25-5)?

2-Chloro-3-nitro-4-pyridinamine is primarily used in the pharmaceutical industry as an intermediate in the synthesis of certain drugs. It also finds applications in the polymer industry for the production of special polymers with specific properties. Additionally, it is used in the semiconductor industry for the fabrication of electronic components.

What precautions should be taken when handling 2-Chloro-3-nitro-4-pyridinamine (CAS: 2789-25-5)?

When handling 2-Chloro-3-nitro-4-pyridinamine, appropriate personal protective equipment (PPE) such as gloves, safety goggles, and a lab coat should be worn. This compound should be managed in a well-ventilated area or a fume hood to minimize exposure. Spills should be handled carefully using appropriate absorbent materials and the manufacturer's safety data sheet (SDS) should be consulted for specific spill cleanup procedures. Storage should be in a cool, dry place away from incompatible substances.