3-(4-Biphenylyl)-3-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}propanoic acid | CAS No. 269078-79-7

3-(4-Biphenylyl)-3-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}propanoic acid

Basic Information

CAS Number

269078-79-7

Molecular Formula

C30H25NO4

Molecular Weight

463.53 g/mol

AD

Basic Physical Properties

C1=CC=C(C=C1)C2=CC=C(C=C2)C(CC(=O)O)NC(=O)OCC3C4=CC=CC=C4C5=CC=CC=C35

InChI

InChI=1S/C30H25NO4/c32-29(33)18-28(22-16-14-21(15-17-22)20-8-2-1-3-9-20)31-30(34)35-19-27-25-12-6-4-10-23(25)24-11-5-7-13-26(24)27/h1-17,27-28H,18-19H2,(H,31,34)(H,32,33)

InChIKey

PEYWNXMITXNNRZ-UHFFFAOYSA-N

LogP

6.4081000000000055

Topological Polar Surface Area

75.63000000000001 Ų

Hydrogen Bond Donor/Acceptor

2 / 5

Complexity

689

Synonyms & References

English

  • AS-66853
  • AB36076
  • SCHEMBL5846051
  • AB36077
  • CS-0345651
  • (R,S)-FMOC-3-AMINO-3-(BIPHENYL)-PROPIONIC ACID
  • Fmoc-(R,S)-3-amino-3-(biphenyl)-propionic acid
  • DTXSID10373272
  • MFCD02179646
  • E70629
  • 3-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(4-phenylphenyl)propanoic Acid
  • (R)-3-BIPHENYL-4-YL-3-(9H-FLUOREN-9-YLMETHOXYCARBONYLAMINO)-PROPIONIC ACID
  • AKOS030242204
  • 3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-(4-phenylphenyl)propanoic acid
  • EN300-81463
  • 3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-([1,1'-biphenyl]-4-yl)propanoic acid
  • 269078-79-7
  • Fmoc-DL-3-(4-diphenyl)-3-amino-propionic acid
  • (R,S)-Fmoc-3-amino-3-(biphenyl)-propionic acid, AldrichCPR
  • 3-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}-3-(4-phenylphenyl)propanoic acid
  • 3-{[1,1'-biphenyl]-4-yl}-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid
  • 3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-([1,1'-biphenyl]-4-yl)propanoicacid
  • Fmoc-(R,S)-3-amino-3-(biphenyl)propionic acid
  • [1,1'-Biphenyl]-4-propanoicacid, b-[[(9H-fluoren-9-ylmethoxy)carbonyl]amino]-
  • 3-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(4-phenylphenyl)propanoic acid
  • FMoc-3-aMino-3-(biphenyl)propionic acid
  • AC1MBSXU
  • CTK8F0736
  • SureCN5846051

MDL Number

MFCD02179646

Customs Code

29225090

FAQ

What are the physical and chemical properties of 3-(4-Biphenylyl)-3-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}propanoic acid (CAS: 269078-79-7)?

3-(4-Biphenylyl)-3-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}propanoic acid (CAS: 269078-79-7) is a white crystalline solid with a molecular weight of approximately 524.5 g/mol. It has a low solubility in water and good solubility in organic solvents like DMSO. It is known for its high reactivity in esterification and amide formation reactions. It exhibits good stability under normal conditions but can degrade under strong acidic or basic conditions.

How is 3-(4-Biphenylyl)-3-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}propanoic acid (CAS: 269078-79-7) typically synthesized?

3-(4-Biphenylyl)-3-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}propanoic acid (CAS: 269078-79-7) is synthesized via multistep reactions involving protecting group chemistry, coupling reactions, and amide formation. Commonly, it is prepared using fluoren-9-ylmethanol as a starting material, followed by acylation and coupling with a biphenyl derivative. The reaction conditions typically include the use of base catalysts like DIPEA and coupling agents such as HATU. The yield is generally around 70-80%.

What industries use 3-(4-Biphenylyl)-3-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}propanoic acid (CAS: 269078-79-7)?

3-(4-Biphenylyl)-3-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}propanoic acid (CAS: 269078-79-7) is primarily used in the pharmaceutical industry for the synthesis of drug intermediates. It also finds applications in the polymer industry for the development of functional polymers. Additionally, it is used in the semiconductor industry for the production of organic light-emitting diodes (OLEDs) and in sensor technology for its unique chemical properties and reactivity.

What precautions should be taken when handling 3-(4-Biphenylyl)-3-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}propanoic acid (CAS: 269078-79-7)?

When handling 3-(4-Biphenylyl)-3-{[(9H-fluoren-9-ylmethoxy)carbonyl]amino}propanoic acid (CAS: 269078-79-7), it is essential to use personal protective equipment (PPE) such as gloves, goggles, and lab coats. The compound should be handled in a well-ventilated fume hood to prevent inhalation. Spills should be cleaned up using appropriate absorbent materials, and the area should be rinsed with water. It is recommended to consult the Safety Data Sheet (SDS) for detailed handling and disposal instructions.

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