L-Alanine, N-(chlorophenoxyphosphinyl)-, 1-methylethyl ester | CAS No. 261909-49-3
L-Alanine, N-(chlorophenoxyphosphinyl)-, 1-methylethyl ester
Basic Information
CAS Number
261909-49-3
Molecular Formula
C12H17ClNO4P
Molecular Weight
305.69 g/mol
AD
Chemical Classification
Basic Physical Properties
Synonyms & References
English
- N-(Chlorophenoxyphosphinyl)-L-alanine 1-methylethyl ester
- isopropyl N-[chloro(phenoxy)phosphoryl]-L-alaninate
- phenyl(isopropoxy-L-alaninyl) phosphorochloridate
- : L-Alanine, N-(chlorophenoxyphosphinyl)-, 1-Methylethyl ester
- isopropyl (2S)-2-[[chloro(phenoxy)phosphoryl]amino]propanoate
- SCHEMBL524067
- 261909-49-3
- propan-2-yl (2S)-2-[[chloro(phenoxy)phosphoryl]amino]propanoate
- Isopropyl (chloro(phenoxy)?phosphoryl)?-?L-?alaninate
- (2S)-isopropyl2-((chloro(phenoxy)phosphoryl)amino)propanoate
- AC-27384
- AKOS025401926
- H11186
- SKAAFTUHFLUIKV-IHBJSSOOSA-N
- CS-0139661
- (2S)-isopropyl 2-((chloro(phenoxy)phosphoryl)amino)propanoate
- isopropyl (2S)-2-{[chloro(phenoxy)phosphoryl]amino}propanoate
- L-Alanine, N-(chlorophenoxyphosphinyl)-, 1-methylethyl ester
MDL Number
MFCD28009496
FAQ
What are the physical and chemical properties of N-(chlorophenoxyphosphinyl)-L-alanine, 1-methylethyl ester (CAS: 261909-49-3)?
N-(chlorophenoxyphosphinyl)-L-alanine, 1-methylethyl ester is a white crystalline solid with a molecular weight of approximately 364.07 g/mol. It is sparingly soluble in water but soluble in common organic solvents such as methanol and ethanol. The compound is reactive towards nucleophiles and can undergo phosphinylation reactions. It is stable under normal storage conditions but should be protected from strong bases and oxidizing agents.
How is N-(chlorophenoxyphosphinyl)-L-alanine, 1-methylethyl ester (CAS: 261909-49-3) typically synthesized?
N-(chlorophenoxyphosphinyl)-L-alanine, 1-methylethyl ester is typically synthesized through a multi-step process involving phosphinylation of L-alanine with chlorophenoxyphosphonic acid, followed by esterification with 1-methylethanol. The reaction is catalyzed by a Lewis acid and proceeds with good selectivity. The overall yield is around 85-90%, and the method is scalable for industrial production.
What industries use N-(chlorophenoxyphosphinyl)-L-alanine, 1-methylethyl ester (CAS: 261909-49-3)?
N-(chlorophenoxyphosphinyl)-L-alanine, 1-methylethyl ester is primarily used in the pharmaceutical industry for the synthesis of new drugs. It is also applied in the polymer industry to enhance material properties and in the sensor industry for developing advanced chemical sensors. Additionally, it has potential applications in the semiconductor industry due to its electronic properties.
What precautions should be taken when handling N-(chlorophenoxyphosphinyl)-L-alanine, 1-methylethyl ester (CAS: 261909-49-3)?
When handling N-(chlorophenoxyphosphinyl)-L-alanine, 1-methylethyl ester, appropriate personal protective equipment (PPE) such as gloves, goggles, and a lab coat is essential. The compound should be handled in a well-ventilated area or a fume hood. Spills should be managed by professional chemical cleaning agents, and the area should be flushed with water. Refer to the Safety Data Sheet (SDS) for detailed emergency response procedures.
Related Compounds
![N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure](https://static.chemtradehub.com/structs/103/103687-96-3-8086.webp "N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine structure")
N-(2-Methoxyphenyl)-N-[(4-methylphenyl)sulfonyl]-beta-alanine
CAS Number:
103687-96-3
Molecular Formula:
C17H19NO5S
![5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure](https://static.chemtradehub.com/structs/112/112897-99-1-d1f4.webp "5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine structure")
5'-O-[Bis(4-methoxyphenyl)(phenyl)methyl]cytidine
CAS Number:
112897-99-1
Molecular Formula:
C30H31N3O7
![(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure](https://static.chemtradehub.com/structs/121/121055-10-5-583d.webp "(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile structure")
(3S,4R)-3-Hydroxy-2,2-dimethyl-4-[(3-oxo-1-cyclopenten-1-yl)oxy]-6-chromanecarbonitrile
CAS Number:
121055-10-5
Molecular Formula:
C17H17NO4
![Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure](https://static.chemtradehub.com/structs/126/1263059-26-2-d6da.webp "Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate structure")
Methyl 5-chloropyrazolo[1,5-a]pyrimidine-2-carboxylate
CAS Number:
1263059-26-2
Molecular Formula:
C8H6ClN3O2
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