Compound Q&A
How is N-(chlorophenoxyphosphinyl)-L-alanine, 1-methylethyl ester (CAS: 261909-49-3) typically synthesized?
Answer
N-(chlorophenoxyphosphinyl)-L-alanine, 1-methylethyl ester is typically synthesized through a multi-step process involving phosphinylation of L-alanine with chlorophenoxyphosphonic acid, followed by esterification with 1-methylethanol. The reaction is catalyzed by a Lewis acid and proceeds with good selectivity. The overall yield is around 85-90%, and the method is scalable for industrial production.
About
CAS No
261909-49-3
English Name
L-Alanine, N-(chlorophenoxyphosphinyl)-, 1-methylethyl ester
Molecular Formula
C12H17ClNO4P
Molecular Weight
305.69 g/mol
SMILES
CC(C)OC(=O)C(C)NP(=O)(OC1=CC=CC=C1)Cl
InChIKey
SKAAFTUHFLUIKV-IHBJSSOOSA-N
Last Updated: 2026-01-07 05:52
