Poly(Propylene Glycol)

Basic Information

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CAS Number

25791-96-2

Molecular Formula

HO(C3H6O)nCH[CH2(OC3H6)nOH]2

Molecular Weight

314.33 g/mol

EINECS

500-044-5

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Physical Properties

Melting Point

-40 °C

Density

1.09 g/mL at 25 °C

Flash Point

>230 °F

Refractive Index

n20/D 1.46

Vapor Pressure

<0.3 mm Hg ( 20 °C)

Vapor Density

>1 (vs air)

SMILES

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OCC(CCOC(OCC(CO)O)OCCC(CO)O)O

InChI

InChI=1S/C12H26O9/c13-5-9(16)1-3-19-12(21-8-11(18)7-15)20-4-2-10(17)6-14/h9-18H,1-8H2

InChIKey

ZSKSVMDBXFSLMZ-UHFFFAOYSA-N

LogP

-0.73 at 25℃

Topological Polar Surface Area

149.07 Å²

Hydrogen Bond Donor/Acceptor

6 / 9

Synonyms & References

English

POLYPROPYLENE GLYCOL 1025
POLYPROPYLENE GLYCOL NO 2,000
POLYPROPYLENE GLYCOL P 1'200
POLYPROPYLENE GLYCOL P 2'000
POLYPROPYLENE GLYCOL 3'250
POLYPROPYLENE GLYCOL TRIOL 4'800
POLYPROPYLENE GLYCOL, TRIOL TYPE
POLYPROPYLENE GLYCOL, TRIOL TYPE, 300
Propoxylated glycerin
Trihydroxy polyoxypropylene ether
Poly propylene glycol glycerol ether
GLYCEROL PROPOXYLATED
bypolet34
bypolet36
gp3000
l-3003
laprol263
laprol503
lg56
niaxlg240
niaxlg56
POLY(PROPYLENE GLYCOL)
propylan3

MDL Number

MFCD00132860

EC Number

500-044-5

FAQ

What are the physical and chemical properties of Poly(Propylene Glycol) (CAS: 25791-96-2)?

Poly(Propylene Glycol) (PPG) is a colorless, odorless, and viscous liquid with a high molecular weight, typically ranging from 200 to 20,000 Da. It is soluble in water and organic solvents. PPG is relatively inert and non-toxic, with limited reactivity towards acids, bases, and oxidizing agents. It crystallizes at temperatures below -70°C and has a low volatility, making it stable under normal conditions.

How is Poly(Propylene Glycol) (CAS: 25791-96-2) typically synthesized?

Poly(Propylene Glycol) (PPG) is synthesized by the polymerization of propylene glycol. This process involves the repeated addition of propylene oxide to propylene glycol in the presence of a catalyst, such as a strong acid or a metal alkoxide. The reaction is typically carried out under anhydrous conditions to ensure high molecular weight and high selectivity, leading to a high yield of PPG.

What industries use Poly(Propylene Glycol) (CAS: 25791-96-2)?

Poly(Propylene Glycol) (PPG) finds extensive use in the pharmaceutical, polymer, and cosmetic industries. It is used as a plasticizer, surfactant, emulsifier, and stabilizer. PPG is also employed in the manufacturing of biocompatible materials, lubricants, and as a carrier in drug delivery systems. Its biocompatibility and low toxicity make it a preferred choice in biomedical applications.

What precautions should be taken when handling Poly(Propylene Glycol) (CAS: 25791-96-2)?

When handling Poly(Propylene Glycol) (PPG), ensure that proper personal protective equipment (PPE) is worn, including gloves, goggles, and a lab coat. Work in a well-ventilated area or a fume hood to avoid inhalation of vapors. Store PPG in tightly sealed containers away from heat sources. In case of a spill, neutralize it with baking soda or similar alkaline substances, then dispose of the waste according to local regulations. Always consult the Material Safety Data Sheet (MSDS) for detailed safety information.