(4-Methoxyphenyl)(4-piperidinyl)methanone hydrochloride (1:1)

Basic Information

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CAS Number

25519-82-8

Molecular Formula

C13H18ClNO2

Molecular Weight

255.74 g/mol

Chemical Classification

Basic Chemical Raw Materials Organic Chemicals Carboxylic Acids

Basic Chemical Raw Materials Organic Chemicals Ketones

Basic Chemical Raw Materials Organic Chemicals Ethers

Basic Chemical Raw Materials Organic Chemicals Heterocyclic Compounds

Pharmaceutical Chemicals Pharmaceutical Intermediates Heterocyclic Intermediates

Fine Chemicals Dyes and Pigments Organic Dyes

Fine Chemicals Surfactants Anionic Surfactants

Agricultural Chemicals Pesticides Herbicides

Basic Physical Properties

Melting Point

251-254 °C

Boiling Point

218.9°C at 760 mmHg

SMILES

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COC1=CC=C(C=C1)C(=O)C2CCNCC2.Cl

InChI

InChI=1S/C13H17NO2.ClH/c1-16-12-4-2-10(3-5-12)13(15)11-6-8-14-9-7-11;/h2-5,11,14H,6-9H2,1H3;1H

InChIKey

BBDTWYQCXXFKDH-UHFFFAOYSA-N

LogP

2.2993000000000006

Topological Polar Surface Area

38.33 Å²

Hydrogen Bond Donor/Acceptor

1 / 3

Complexity

228

Safety Information

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Hazard Statement

H302 Harmful if swallowed
Acute toxicity, oral

H315 Causes skin irritation
Skin corrosion/irritation

H319 Causes serious eye irritation
Serious eye damage/eye irritation

H332 Harmful if inhaled
Acute toxicity, inhalation

H335 May cause respiratory irritation
Specific target organ toxicity, single exposure; Respiratory tract irritation

Synonyms & References

English

4-(4-METHOXYBENZOYL)PIPERIDINE HCL
4-(4-Methoxybenzoyl)-piperidine hydrochloride
SY022090
4-[(4-methoxyphenyl)carbonyl]piperidine hydrochloride
CS-W002379
SCHEMBL518416
Methanone, (4-methoxyphenyl)-4-piperidinyl-, hydrochloride
AC-25674
(4-methoxyphenyl)-piperidin-4-ylmethanone;hydrochloride
4-(4-Methoxybenzoyl)piperidine hydrochloride
(4-Methoxyphenyl)(4-piperidyl)-methanone hydrochloride
AKOS015849529
SS-4719
SB36216
(4-Methoxy-phenyl)-piperidin-4-yl-methanone hydrochloride
4-(4-Methoxybenzoyl)piperidinehydrochloride
BBDTWYQCXXFKDH-UHFFFAOYSA-N
Methanone, (4-methoxyphenyl)-4-piperidinyl-, hydrochloride (1:1); Ketone, p-methoxyphenyl 4-piperidyl, hydrochloride (8CI); Methanone, (4-methoxyphenyl)-4-piperidinyl-, hydrochloride (9CI); 4-(4-Methoxybenzoyl)piperidine hydrochloride; 4-(p-Methoxybenzoyl)piperidine hydrochloride
FT-0604781
(4-methoxyphenyl)(4-piperidyl)methanone hydrochloride, AldrichCPR
J-501420
Methanone,(4-methoxyphenyl)-4-piperidinyl-,HCl
AM20040036
(4-methoxyphenyl)(4-piperidyl)methanone hydrochloride
A24550
(4-Methoxyphenyl)(piperidin-4-yl)methanone hydrochloride
MFCD00114817
(4-Methoxyphenyl)(4-piperidyl)methanone, HCl
EN300-30360
25519-82-8
DTXSID10372381

MDL Number

MFCD00114817

Customs Code

2933399090

FAQ

What are the physical and chemical properties of (4-Methoxyphenyl)(4-piperidinyl)methanone hydrochloride (CAS: 25519-82-8)?

(4-Methoxyphenyl)(4-piperidinyl)methanone hydrochloride is a crystalline compound with a molecular weight of approximately 322.37 g/mol. It has a hydrochloride salt form, which increases its solubility in water. This compound is slightly soluble in water and organic solvents. It shows moderate reactivity, particularly towards basic conditions. It is stable under normal storage conditions but should be protected from moisture and air to prevent hydrolysis.

How is (4-Methoxyphenyl)(4-piperidinyl)methanone hydrochloride (CAS: 25519-82-8) typically synthesized?

(4-Methoxyphenyl)(4-piperidinyl)methanone hydrochloride is typically synthesized through a multi-step process involving the reaction of 4-methoxybenzaldehyde with 4-piperidinecarboxaldehyde, followed by treatment with hydrochloric acid. This method provides good yield and high selectivity, making it a reliable synthesis approach for this compound.

What industries use (4-Methoxyphenyl)(4-piperidinyl)methanone hydrochloride (CAS: 25519-82-8)?

(4-Methoxyphenyl)(4-piperidinyl)methanone hydrochloride finds applications in the pharmaceutical industry, where it serves as a precursor for the synthesis of certain drugs. It is also used in the polymer industry for its potential as a stabilizer or modifier. Additionally, it has some applications in sensors and as a component in the development of certain semiconductor materials.

What precautions should be taken when handling (4-Methoxyphenyl)(4-piperidinyl)methanone hydrochloride (CAS: 25519-82-8)?

When handling (4-Methoxyphenyl)(4-piperidinyl)methanone hydrochloride, it is essential to wear appropriate personal protective equipment (PPE), including gloves, safety goggles, and a lab coat. Work should be conducted in a well-ventilated fume hood to minimize inhalation risks. Spills should be cleaned up with caution using appropriate absorbent materials. Refer to the Material Safety Data Sheet (MSDS) or Safety Data Sheet (SDS) for specific spill and disposal instructions. Storage should be in a cool, dry place, away from moisture and heat sources.